Cellosaurus cell line AKI (CVCL

Cellosaurus AKI (CVCL_8170)

Cross-references
Cell line name	AKI
Accession	CVCL_8170
Resource Identification Initiative	To cite this cell line use: AKI (RRID:CVCL_8170)
Comments	Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=16643607; PubMed=20143388). Originally thought to originate from a 42 year old male patient with a melanoma. Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00172. Population: African American. Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18). Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease	Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_0030 (HeLa)
Sex of cell	Female
Age at sampling	30Y6M
Category	Cancer cell line
Web pages	https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications	PubMed=3145150 Ishii A., Matsui M., Terano Y., Miura Y. Establishment and characterization of a novel human malignant melanoma cell line AKI. Cell. Mol. Biol. 34:255-264(1988) PubMed=16643607; DOI=10.1111/j.1749-0774.2005.00007.x Yoshino K., Iimura E., Saijo K., Iwase S., Fukami K., Ohno T., Obata Y., Nakamura Y. Essential role for gene profiling analysis in the authentication of human cell lines. Hum. Cell 19:43-48(2006) PubMed=20143388; DOI=10.1002/ijc.25242 Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I. Check your cultures! A list of cross-contaminated or misidentified cell lines. Int. J. Cancer 127:1-8(2010)
Cell line collections (Providers)	RCB; RCB0408 - Discontinued
Biological sample resources	BioSample; SAMN03151663
Encyclopedic resources	Wikidata; Q54749095
Polymorphism and mutation databases	IARC_TP53; 21172
Entry history
Entry creation	04-Apr-2012
Last entry update	02-May-2024
Version number	23