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Cellosaurus HN-2 (CVCL_8125)

[Text version]
Cell line name HN-2
Synonyms HN2; LICR-LON-HN2; LICR (LON) HN2; LICR(Lond)-HN 2; LICR-HN2
Accession CVCL_8125
Resource Identification Initiative To cite this cell line use: HN-2 (RRID:CVCL_8125)
Comments Doubling time: 48 hours (PubMed=7195729).
Derived from site: In situ; Larynx; UBERON=UBERON_0001737.
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_LI54 (LICR-HN2 R10.3)
Sex of cell Male
Age at sampling 49Y
Category Cancer cell line
Publications

PubMed=7195729; DOI=10.1038/bjc.1981.115; PMCID=PMC2010719
Easty D.M., Easty G.C., Carter R.L., Monaghan P., Butler L.J.
Ten human carcinoma cell lines derived from squamous carcinomas of the head and neck.
Br. J. Cancer 43:772-785(1981)

PubMed=6387708; DOI=10.1073/pnas.81.21.6632; PMCID=PMC391984
Pfyffer G.E., Haemmerli G., Heizmann C.W.
Calcium-binding proteins in human carcinoma cell lines.
Proc. Natl. Acad. Sci. U.S.A. 81:6632-6636(1984)

PubMed=2427339; DOI=10.1016/0277-5379(86)90158-6
Easty D.M., Easty G.C., Baici A., Carter R.L., Cederholm-Williams S.A., Felix H., Gusterson B.A., Haemmerli G., Hauser-Urfer I.H., Heizmann C.W., Mareel M.M., Stehrenberger B., Strauli P.
Biological studies of ten human squamous carcinoma cell lines: an overview.
Eur. J. Cancer Clin. Oncol. 22:617-634(1986)

DOI=10.1016/B978-0-12-333530-2.50007-1
Carey T.E.
Head and neck tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York; USA (1994)

PubMed=26032726; DOI=10.1186/s13104-015-1197-6; PMCID=PMC4467624
Boeckx C., Van den Bossche J., De Pauw I., Peeters M., Lardon F., Baay M., Wouters A.
The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines.
BMC Res. Notes 8:203.1-203.6(2015)

PubMed=26269754; PMCID=PMC4529614
Boeckx C., Blockx L., Op de Beeck K., Limame R., Van Camp G., Peeters M., Vermorken J.B., Specenier P., Wouters A., Baay M., Lardon F.
Establishment and characterization of cetuximab resistant head and neck squamous cell carcinoma cell lines: focus on the contribution of the AP-1 transcription factor.
Am. J. Cancer Res. 5:1921-1938(2015)

Cross-references
Encyclopedic resources Wikidata; Q54889990
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number16