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Cellosaurus 1479-mel (CVCL_8047)

[Text version]
Cell line name 1479-mel
Synonyms 1479-MEL; 1479 mel; 1479; Mel-1479
Accession CVCL_8047
Resource Identification Initiative To cite this cell line use: 1479-mel (RRID:CVCL_8047)
Comments From: Rosenberg, Steven A.; Surgery Branch, National Cancer Institute, National Institutes of Health; Bethesda; USA.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Unspecified (PubMed=23851445).
  • Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23851445).
  • Mutation; HGNC; HGNC:8979; PIK3R1; Simple; p.Asp464_Tyr467del (c.1392_1403del); Zygosity=Unspecified (PubMed=23851445).
HLA typing Source: PubMed=10048982
Class I
HLA-AA*02,03
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): ESTDAB=ESTDAB-048

Markers:
AmelogeninX
CSF1PO10
D3S135814,15
D5S81812
D7S82010,13
D13S3179
FGA21
TH019.3
TPOX8
vWA17

Run an STR similarity search on this cell line
Publications

PubMed=10048982; DOI=10.1002/(SICI)1097-0215(19990301)80:5<781::AID-IJC24>3.0.CO;2-A; PMCID=PMC2072935
Cormier J.N., Panelli M.C., Hackett J.A., Bettinotti M.P., Mixon A., Wunderlich J.R., Parker L.L., Restifo N.P., Ferrone S., Marincola F.M.
Natural variation of the expression of HLA and endogenous antigen modulates CTL recognition in an in vitro melanoma model.
Int. J. Cancer 80:781-790(1999)

PubMed=19340423; DOI=10.1007/s00262-009-0701-z; PMCID=PMC11030131
Mendez R., Aptsiauri N., Del Campo A., Maleno I., Cabrera T., Ruiz-Cabello Osuna F., Garrido F., Garcia-Lora A.
HLA and melanoma: multiple alterations in HLA class I and II expression in human melanoma cell lines from ESTDAB cell bank.
Cancer Immunol. Immunother. 58:1507-1515(2009)

PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006
Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L., Borg A., Pawelec G., Guldberg P.
Mutual exclusivity analysis of genetic and epigenetic drivers in melanoma identifies a link between p14 ARF and RARbeta signaling.
Mol. Cancer Res. 11:1166-1178(2013)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8047
ESTDAB; ESTDAB-048
Encyclopedic resources Wikidata; Q54581931
Polymorphism and mutation databases Cosmic; 2163792
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number21