ID   TTC-549
AC   CVCL_8005
SY   TTC549
DR   EFO; EFO_0005700
DR   BioSample; SAMN10989627
DR   Cell_Model_Passport; SIDM01457
DR   Cosmic; 801776
DR   Cosmic; 802052
DR   Cosmic; 1063888
DR   Cosmic; 2144784
DR   DepMap; ACH-001211
DR   ENCODE; ENCBS258AAA
DR   GEO; GSM3145740
DR   Wikidata; Q54973250
RX   PubMed=8818656;
RX   PubMed=9559292;
RX   PubMed=9920784;
RX   PubMed=10602515;
RX   PubMed=11557780;
RX   PubMed=11921280;
RX   PubMed=12210830;
RX   PubMed=16557275;
RX   PubMed=24418192;
RX   PubMed=31068700;
WW   http://genome.ucsc.edu/ENCODE/protocols/cell/human/MRTTTC549_Crawford_protocol.pdf
CC   Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE).
CC   Part of: ENCODE project common cell types; tier 3.
CC   Sequence variation: Gene deletion; HGNC; 11103; SMARCB1; Zygosity=Homozygous (PubMed=10602515; PubMed=11921280).
CC   Omics: Deep exome analysis.
CC   Omics: SNP array analysis.
CC   Derived from site: In situ; Liver; UBERON=UBERON_0002107.
DI   NCIt; C6586; Extrarenal rhabdoid tumor
DI   ORDO; Orphanet_69077; Rhabdoid tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   6M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 29-06-23; Version: 24
//
RX   PubMed=8818656; DOI=10.1002/(SICI)1098-2264(199606)16:2<94::AID-GCC3>3.0.CO;2-Y;
RA   Biegel J.A., Allen C.S., Kawasaki K., Shimizu N., Budarf M.L.,
RA   Bell C.J.;
RT   "Narrowing the critical region for a rhabdoid tumor locus in 22q11.";
RL   Genes Chromosomes Cancer 16:94-105(1996).
//
RX   PubMed=9559292; DOI=10.1097/00019606-199712000-00004;
RA   Suzuki A., Ohta S., Shimada M.;
RT   "Gene expression of malignant rhabdoid tumor cell lines by reverse
RT   transcriptase-polymerase chain reaction.";
RL   Diagn. Mol. Pathol. 6:326-332(1997).
//
RX   PubMed=9920784; DOI=10.1006/bbrc.1998.9968;
RA   Mori T., Fukuda Y., Kuroda H., Matsumura T., Ota S., Sugimoto T.,
RA   Nakamura Y., Inazawa J.;
RT   "Cloning and characterization of a novel Rab-family gene, Rab36,
RT   within the region at 22q11.2 that is homozygously deleted in malignant
RT   rhabdoid tumors.";
RL   Biochem. Biophys. Res. Commun. 254:594-600(1999).
//
RX   PubMed=10602515; DOI=10.1038/sj.onc.1203168;
RA   DeCristofaro M.F., Betz B.L., Wang W.-D., Weissman B.E.;
RT   "Alteration of hSNF5/INI1/BAF47 detected in rhabdoid cell lines and
RT   primary rhabdomyosarcomas but not Wilms' tumors.";
RL   Oncogene 18:7559-7565(1999).
//
RX   PubMed=11557780; DOI=10.1038/modpathol.3880401;
RA   Itakura E., Tamiya S., Morita K., Shiratsuchi H., Kinoshita Y.,
RA   Oshiro Y., Oda Y., Ohta S., Furue M., Tsuneyoshi M.;
RT   "Subcellular distribution of cytokeratin and vimentin in malignant
RT   rhabdoid tumor: three-dimensional imaging with confocal laser scanning
RT   microscopy and double immunofluorescence.";
RL   Mod. Pathol. 14:854-861(2001).
//
RX   PubMed=11921280; DOI=10.1002/gcc.10052;
RA   Uno K., Takita J., Yokomori K., Tanaka Y., Ohta S., Shimada H.,
RA   Gilles F.H., Sugita K., Abe S., Sako M., Hashizume K., Hayashi Y.;
RT   "Aberrations of the hSNF5/INI1 gene are restricted to malignant
RT   rhabdoid tumors or atypical teratoid/rhabdoid tumors in pediatric
RT   solid tumors.";
RL   Genes Chromosomes Cancer 34:33-41(2002).
//
RX   PubMed=12210830; DOI=10.1002/jnr.10330;
RA   Yoshida S., Narita T., Taga T., Ohta S., Takeuchi Y.;
RT   "Malignant rhabdoid tumor shows incomplete neural characteristics as
RT   revealed by expression of SNARE complex.";
RL   J. Neurosci. Res. 69:642-652(2002).
//
RX   PubMed=16557275; DOI=10.1038/modpathol.3800599;
RA   Izumi T., Oda Y., Hasegawa T., Nakanishi Y., Iwasaki H., Sonobe H.,
RA   Goto H., Kusakabe H., Takahira T., Kobayashi C., Kawaguchi K.-i.,
RA   Saito T., Yamamoto H., Tamiya S., Iwamoto Y., Tsuneyoshi M.;
RT   "Prognostic significance of dysadherin expression in epithelioid
RT   sarcoma and its diagnostic utility in distinguishing epithelioid
RT   sarcoma from malignant rhabdoid tumor.";
RL   Mod. Pathol. 19:820-831(2006).
//
RX   PubMed=24418192; DOI=10.1111/cas.12352;
RA   Takita J., Chen Y.-Y., Kato M., Ohki K., Sato Y., Ohta S., Sugita K.,
RA   Nishimura R., Hoshino N., Seki M., Sanada M., Oka A., Hayashi Y.,
RA   Ogawa S.;
RT   "Genome-wide approach to identify second gene targets for malignant
RT   rhabdoid tumors using high-density oligonucleotide microarrays.";
RL   Cancer Sci. 105:258-264(2014).
//
RX   PubMed=31068700; DOI=10.1038/s41586-019-1186-3;
RA   Ghandi M., Huang F.W., Jane-Valbuena J., Kryukov G.V., Lo C.C.,
RA   McDonald E.R. III, Barretina J.G., Gelfand E.T., Bielski C.M., Li H.-X.,
RA   Hu K., Andreev-Drakhlin A.Y., Kim J., Hess J.M., Haas B.J., Aguet F.,
RA   Weir B.A., Rothberg M.V., Paolella B.R., Lawrence M.S., Akbani R.,
RA   Lu Y.-L., Tiv H.L., Gokhale P.C., de Weck A., Mansour A.A., Oh C.,
RA   Shih J., Hadi K., Rosen Y., Bistline J., Venkatesan K., Reddy A.,
RA   Sonkin D., Liu M., Lehar J., Korn J.M., Porter D.A., Jones M.D.,
RA   Golji J., Caponigro G., Taylor J.E., Dunning C.M., Creech A.L.,
RA   Warren A.C., McFarland J.M., Zamanighomi M., Kauffmann A.,
RA   Stransky N., Imielinski M., Maruvka Y.E., Cherniack A.D.,
RA   Tsherniak A., Vazquez F., Jaffe J.D., Lane A.A., Weinstock D.M.,
RA   Johannessen C.M., Morrissey M.P., Stegmeier F., Schlegel R.,
RA   Hahn W.C., Getz G., Mills G.B., Boehm J.S., Golub T.R., Garraway L.A.,
RA   Sellers W.R.;
RT   "Next-generation characterization of the Cancer Cell Line
RT   Encyclopedia.";
RL   Nature 569:503-508(2019).
//