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Cellosaurus SP-6.5 (CVCL_7997)

[Text version]
Cell line name SP-6.5
Synonyms SP 6.5; SP6.5; SP6_5
Accession CVCL_7997
Resource Identification Initiative To cite this cell line use: SP-6.5 (RRID:CVCL_7997)
Comments Omics: Transcriptomics; Microarray.
Derived from site: In situ; Eye, uvea; UBERON=UBERON_0001768.
Sequence variations
Disease Uveal melanoma (NCIt: C7712)
Uveal melanoma (ORDO: Orphanet_39044)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 77Y
Category Cancer cell line
Publications

PubMed=9154388; DOI=10.1076/ceyr.16.5.487.7047
Diebold Y., Blanco G., Saornil-Alvarez M.A., Fernandez N., Lazaro M.C.
Morphologic and immunocytochemical characterization of four human uveal cell lines (melanoma- and melanocytes-derived).
Curr. Eye Res. 16:487-495(1997)

PubMed=10892885
Beliveau A., Berube M., Rousseau A.P., Pelletier G., Guerin S.L.
Expression of integrin alpha5beta1 and MMPs associated with epithelioid morphology and malignancy of uveal melanoma.
Invest. Ophthalmol. Vis. Sci. 41:2363-2372(2000)

PubMed=15645125; DOI=10.3892/ijo.26.2.405
Berube M., Talbot M., Collin C., Paquet-Bouchard C., Germain L., Guerin S.L., Petitclerc E.
Role of the extracellular matrix proteins in the resistance of SP6.5 uveal melanoma cells toward cisplatin.
Int. J. Oncol. 26:405-413(2005)

PubMed=15714118; DOI=10.1097/00008390-200502000-00006
Lopez-Velasco R., Morilla-Grasa A., Saornil-Alvarez M.A., Ordonez J.L., Blanco G., Rabano G., Fernandez N., Almaraz A.
Efficacy of five human melanocytic cell lines in experimental rabbit choroidal melanoma.
Melanoma Res. 15:29-37(2005)

PubMed=17487557; DOI=10.1007/s10585-007-9072-z
Marshall J.-C., Nantel A., Blanco P., Ash J., Cruess S.R., Burnier M.N. Jr.
Transcriptional profiling of human uveal melanoma from cell lines to intraocular tumors to metastasis.
Clin. Exp. Metastasis 24:353-362(2007)

PubMed=22236444; DOI=10.1111/j.1755-148X.2012.00971.x; PMCID=PMC3288394
Griewank K.G., Yu X.-X., Khalili J.S., Sozen M.M., Stempke-Hale K., Bernatchez C., Wardell S., Bastian B.C., Woodman S.E.
Genetic and molecular characterization of uveal melanoma cell lines.
Pigment Cell Melanoma Res. 25:182-187(2012)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7997
Anatomy/cell type resources BTO; BTO_0002737
Encyclopedic resources Wikidata; Q54955390
Polymorphism and mutation databases Cosmic; 986620
Cosmic; 1628411
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number22