ID   KP-L-RY
AC   CVCL_7984
SY   KPL-RY; K.P.L.RY; KPLRY; Kyoto Pediatrics-Leukemia-RY
DR   EFO; EFO_0022444
DR   Cosmic; 2378133
DR   Wikidata; Q54900380
RX   PubMed=10739008;
RX   PubMed=11226526;
RX   PubMed=12399976;
RX   PubMed=14671638;
CC   Population: Japanese.
CC   Microsatellite instability: Stable (MSS) (PubMed=10739008; PubMed=11226526).
CC   Sequence variation: Gene fusion; HGNC; HGNC:17869; AFF4 + HGNC; HGNC:7132; KMT2A; Name(s)=KMT2A-AFF4, MLL-AF5Q31 (PubMed=12399976; PubMed=14671638).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C9140; Childhood B acute lymphoblastic leukemia
DI   NCIt; C80342; B acute lymphoblastic leukemia with t(v;11q23.3) MLL rearranged
DI   ORDO; Orphanet_585918; B-lymphoblastic leukemia/lymphoma with t(v;11q23.3)
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   1M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 20
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RX   PubMed=10739008; DOI=10.1016/S0145-2126(99)00182-4;
RA   Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.;
RT   "Frequent microsatellite instability and BAX mutations in T cell acute
RT   lymphoblastic leukemia cell lines.";
RL   Leuk. Res. 24:255-262(2000).
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RX   PubMed=11226526; DOI=10.1016/S0145-2126(00)00121-1;
RA   Inoue K., Kohno T., Takakura S., Hayashi Y., Mizoguchi H., Yokota J.;
RT   "Corrigendum to: Frequent microsatellite instability and BAX mutations
RT   in T cell acute lymphoblastic leukemia cell lines Leukemia Research 24
RT   (2000), 255-262.";
RL   Leuk. Res. 25:275-278(2001).
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RX   PubMed=12399976; DOI=10.1038/sj.leu.2402665;
RA   Imamura T., Morimoto A., Ikushima S., Kakazu N., Hada S., Tabata Y.,
RA   Yagi T., Inaba T., Hibi S., Sugimoto T., Imashuku S.;
RT   "A novel infant acute lymphoblastic leukemia cell line with MLL-AF5q31
RT   fusion transcript.";
RL   Leukemia 16:2302-2308(2002).
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RX   PubMed=14671638; DOI=10.1038/sj.leu.2403236;
RA   Drexler H.G., Quentmeier H., MacLeod R.A.F.;
RT   "Malignant hematopoietic cell lines: in vitro models for the study of
RT   MLL gene alterations.";
RL   Leukemia 18:227-232(2004).
//