ID   KOPN-57bi
AC   CVCL_7978
SY   KOPN57bi
DR   IARC_TP53; 28423
DR   Wikidata; Q54900313
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=10071072;
RX   PubMed=10360377;
RX   PubMed=10942233;
RX   PubMed=10995006;
RX   PubMed=12506034;
RX   PubMed=20519628;
RX   PubMed=20575032;
RX   PubMed=28569787;
RX   PubMed=29786757;
RX   PubMed=35124168;
CC   Population: Japanese.
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL (PubMed=10071072; PubMed=12506034).
CC   Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
DI   NCIt; C68659; Childhood B acute lymphoblastic leukemia with t(9;22)(q34.1;q11.2) BCR-ABL1
DI   ORDO; Orphanet_585909; B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   11Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 16
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4;
RA   Drexler H.G., MacLeod R.A.F., Uphoff C.C.;
RT   "Leukemia cell lines: in vitro models for the study of Philadelphia
RT   chromosome-positive leukemia.";
RL   Leuk. Res. 23:207-215(1999).
//
RX   PubMed=10360377; DOI=10.1038/sj.leu.2401437;
RA   Nakamura M., Sugita K., Inukai T., Goi K., Iijima K., Tezuka T.,
RA   Kojika S., Shiraishi K., Miyamoto N., Karakida N., Kagami K.,
RA   Koyama-Okazaki T., Mori T., Nakazawa S.;
RT   "p16/MTS1/INK4A gene is frequently inactivated by hypermethylation in
RT   childhood acute lymphoblastic leukemia with 11q23 translocation.";
RL   Leukemia 13:884-890(1999).
//
RX   PubMed=10942233; DOI=10.1038/sj.leu.2401837;
RA   Inukai T., Sugita K., Mitsui K., Iijima K., Goi K., Tezuka T.,
RA   Kojika S., Kagami K., Mori T., Kinoshita A., Suzuki T.,
RA   Koyama-Okazaki T., Nakazawa S.;
RT   "Participation of granulocyte colony-stimulating factor in the growth
RT   regulation of leukemia cells from Philadelphia chromosome-positive
RT   acute leukemia and blast crisis of chronic myeloid leukemia.";
RL   Leukemia 14:1386-1395(2000).
//
RX   PubMed=10995006; DOI=10.1038/sj.leu.2401893;
RA   Iijima K., Sugita K., Inukai T., Goi K., Tezuka T., Uno K., Sato H.,
RA   Kagami K., Nakazawa S.;
RT   "Expression of thrombopoietin receptor and its functional role in
RT   human B-precursor leukemia cells with 11q23 translocation or
RT   Philadelphia chromosome.";
RL   Leukemia 14:1598-1605(2000).
//
RX   PubMed=12506034; DOI=10.1182/blood-2002-06-1770;
RA   Uno K., Inukai T., Kayagaki N., Goi K., Sato H., Nemoto A.,
RA   Takahashi K., Kagami K., Yamaguchi N., Yagita H., Okumura K.,
RA   Koyama-Okazaki T., Suzuki T., Sugita K., Nakazawa S.;
RT   "TNF-related apoptosis-inducing ligand (TRAIL) frequently induces
RT   apoptosis in Philadelphia chromosome-positive leukemia cells.";
RL   Blood 101:3658-3667(2003).
//
RX   PubMed=20519628; DOI=10.1182/blood-2009-09-244673;
RA   Hirose K., Inukai T., Kikuchi J., Furukawa Y., Ikawa T., Kawamoto H.,
RA   Oram S.H., Gottgens B., Kiyokawa N., Miyagawa Y., Okita H.,
RA   Akahane K., Zhang X.-C., Kuroda I., Honna H., Kagami K., Goi K.,
RA   Kurosawa H., Look A.T., Matsui H., Inaba T., Sugita K.;
RT   "Aberrant induction of LMO2 by the E2A-HLF chimeric transcription
RT   factor and its implication in leukemogenesis of B-precursor ALL with
RT   t(17;19).";
RL   Blood 116:962-970(2010).
//
RX   PubMed=20575032; DOI=10.1002/ajh.21738; PMCID=PMC7159455;
RA   Inukai T., Zhang X.-R., Kameyama T., Suzuki Y., Yoshikawa K., Kuroda I.,
RA   Nemoto A., Akahane K., Sato H., Goi K., Nakamoto K., Hamada J.-i.,
RA   Tada M., Moriuchi T., Sugita K.;
RT   "A specific linkage between the incidence of TP53 mutations and type
RT   of chromosomal translocations in B-precursor acute lymphoblastic
RT   leukemia cell lines.";
RL   Am. J. Hematol. 85:535-537(2010).
//
RX   PubMed=28569787; DOI=10.1038/cddis.2017.249; PMCID=PMC5520907;
RA   Kasai S., Furuichi Y., Ando N., Kagami K., Abe M., Nakane T., Goi K.,
RA   Inukai T., Saitoh S., Ohno S., Okazaki S., Nagano O., Saya H.,
RA   Sugita K.;
RT   "Inflammatory mediator ultra-low-molecular-weight hyaluronan triggers
RT   necrosis of B-precursor leukemia cells with high surface CD44
RT   expression.";
RL   Cell Death Dis. 8:e2857.1-e2857.11(2017).
//
RX   PubMed=29786757; DOI=10.1007/s12185-018-2474-7;
RA   Tomoyasu C., Imamura T., Tomii T., Yano M., Asai D., Goto H.,
RA   Shimada A., Sanada M., Iwamoto S., Takita J., Minegishi M., Inukai T.,
RA   Sugita K., Hosoi H.;
RT   "Copy number abnormality of acute lymphoblastic leukemia cell lines
RT   based on their genetic subtypes.";
RL   Int. J. Hematol. 108:312-318(2018).
//
RX   PubMed=35124168; DOI=10.1016/j.jsbmb.2022.106068;
RA   Tamai M., Kasai S., Akahane K., Thu T.N., Kagami K., Komatsu C.,
RA   Abe M., Watanabe A., Goi K., Miyake K., Inaba T., Takita J., Goto H.,
RA   Minegishi M., Iwamoto S., Sugita K., Inukai T.;
RT   "Glucocorticoid receptor gene mutations confer glucocorticoid
RT   resistance in B-cell precursor acute lymphoblastic leukemia.";
RL   J. Steroid Biochem. Mol. Biol. 218:106068.1-106068.12(2022).
//