ID   KOPM-28
AC   CVCL_7973
SY   KOPM28
DR   Cosmic; 787497
DR   Wikidata; Q54900295
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RX   PubMed=3494166;
RX   PubMed=10071072;
RX   PubMed=10576511;
RX   PubMed=12506034;
CC   Population: Japanese.
CC   Sequence variation: Gene fusion; HGNC; HGNC:76; ABL1 + HGNC; HGNC:1014; BCR; Name(s)=BCR-ABL1, BCR-ABL; Note=BCR exon 14 fused to ABL1 exon 2 (b3a2 transcript) (PubMed=10071072; PubMed=10576511; PubMed=12506034).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C3174; Chronic myelogenous leukemia, BCR-ABL1 positive
DI   ORDO; Orphanet_521; Chronic myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   64Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 15
//
RX   DOI=10.1016/B978-0-12-221970-2.50457-5;
RA   Drexler H.G.;
RT   "The leukemia-lymphoma cell line factsbook.";
RL   (In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001).
//
RX   PubMed=3494166; DOI=10.1016/0145-2126(87)90047-6;
RA   Mori T., Nakazawa S., Nishino K., Sugita K., Takane K., Mori M.,
RA   Sagawa K., Hayashi Y., Sakurai M.;
RT   "Ph1-positive CML-derived myeloid-monocytoid precursor cell line
RT   producing substance(s) that stimulates normal CFU-C.";
RL   Leuk. Res. 11:241-249(1987).
//
RX   PubMed=10071072; DOI=10.1016/S0145-2126(98)00171-4;
RA   Drexler H.G., MacLeod R.A.F., Uphoff C.C.;
RT   "Leukemia cell lines: in vitro models for the study of Philadelphia
RT   chromosome-positive leukemia.";
RL   Leuk. Res. 23:207-215(1999).
//
RX   PubMed=10576511; DOI=10.1016/S0145-2126(99)00131-9;
RA   Uphoff C.C., Habig S., Fombonne S., Matsuo Y., Drexler H.G.;
RT   "ABL-BCR expression in BCR-ABL-positive human leukemia cell lines.";
RL   Leuk. Res. 23:1055-1060(1999).
//
RX   PubMed=12506034; DOI=10.1182/blood-2002-06-1770;
RA   Uno K., Inukai T., Kayagaki N., Goi K., Sato H., Nemoto A.,
RA   Takahashi K., Kagami K., Yamaguchi N., Yagita H., Okumura K.,
RA   Koyama-Okazaki T., Suzuki T., Sugita K., Nakazawa S.;
RT   "TNF-related apoptosis-inducing ligand (TRAIL) frequently induces
RT   apoptosis in Philadelphia chromosome-positive leukemia cells.";
RL   Blood 101:3658-3667(2003).
//