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Cellosaurus KMCH-2 (CVCL_7971)

[Text version]
Cell line name KMCH-2
Accession CVCL_7971
Resource Identification Initiative To cite this cell line use: KMCH-2 (RRID:CVCL_7971)
Comments Population: Japanese.
Doubling time: ~44 hours (Note=At 20th passage), ~32 hours (Note=At 55th passage) (PubMed=8738727).
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Combined hepatocellular carcinoma and cholangiocarcinoma (NCIt: C3828)
Combined hepatocellular carcinoma and cholangiocarcinoma (ORDO: Orphanet_529852)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 40Y
Category Cancer cell line
Publications

PubMed=7537711; DOI=10.1002/hep.1840210510
Haramaki M., Yano H., Fukuda K., Momosaki S., Ogasawara S., Kojiro M.
Expression of CD44 in human hepatocellular carcinoma cell lines.
Hepatology 21:1276-1284(1995)

PubMed=8738727; DOI=10.1016/S0168-8278(96)80161-9
Yano H., Iemura A., Haramaki M., Momosaki S., Ogasawara S., Higaki K., Kojiro M.
A human combined hepatocellular and cholangiocarcinoma cell line (KMCH-2) that shows the features of hepatocellular carcinoma or cholangiocarcinoma under different growth conditions.
J. Hepatol. 24:413-422(1996)

PubMed=10347112; DOI=10.1002/hep.510290624
Yano H., Iemura A., Haramaki M., Ogasawara S., Takayama A., Akiba J., Kojiro M.
Interferon alfa receptor expression and growth inhibition by interferon alfa in human liver cancer cell lines.
Hepatology 29:1708-1717(1999)

CLPUB00275
Zach S., Birgin E., Ruckert F.
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y., Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S., Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Encyclopedic resources Wikidata; Q54900109
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number15