Cellosaurus logo
expasy logo

Cellosaurus UT-SCC-46A (CVCL_7853)

[Text version]
Cell line name UT-SCC-46A
Synonyms University of Turku-Squamous Cell Carcinoma-46A
Accession CVCL_7853
Resource Identification Initiative To cite this cell line use: UT-SCC-46A (RRID:CVCL_7853)
Comments Omics: Deep exome analysis.
Derived from site: In situ; Oral cavity, gingiva; UBERON=UBERON_0001828.
Disease Gingival squamous cell carcinoma (NCIt: C129857)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7854 ! UT-SCC-46B
Sex of cell Male
Age at sampling 62Y
Category Cancer cell line
STR profile Source(s): PubMed=30135316

Markers:
AmelogeninX,Y
CSF1PO10,11
D2S133820
D3S135816
D5S81811
D7S82010,12
D8S117914,15
D13S3179,14
D16S53911
D18S5113,15
D19S43313,14
D21S1129,30
FGA22,24
TH019,9.3
TPOX8
vWA16,17,18

Run an STR similarity search on this cell line
Publications

PubMed=15287027; DOI=10.1002/gcc.20066
Takebayashi S., Hickson A., Ogawa T., Jung K.-Y., Mineta H., Ueda Y., Grenman R., Fisher S.G., Carey T.E.
Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer.
Genes Chromosomes Cancer 41:145-154(2004)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174
Jamieson S.M.F., Tsai P., Kondratyev M.K., Budhani P., Liu A., Senzer N.N., Chiorean E.G., Jalal S.I., Nemunaitis J.J., Kee D., Shome A., Wong W.W., Li D., Poonawala-Lohani N., Kakadia P.M., Knowlton N.S., Lynch C.R.H., Hong C.R., Lee T.W., Grenman R., Caporiccio L., McKee T.D., Zaidi M., Butt S., Macann A.M.J., McIvor N.P., Chaplin J.M., Hicks K.O., Bohlander S.K., Wouters B.G., Hart C.P., Print C.G., Wilson W.R., Curran M.A., Hunter F.W.
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
JCI Insight 3:e122204.1-e122204.19(2018)

DOI=10.1158/1538-7445.AM2020-507
Kondratyev M.K., Pesic A., Dvorkin-Sheva A., Ketela T., Moffat J., Koritzinsky M., Wouters B.G.
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Encyclopedic resources Wikidata; Q54992136
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number11