Cellosaurus cell line UT-SCC-30 (CVCL

Cellosaurus UT-SCC-30 (CVCL_7834)

Cross-references
Cell line name	UT-SCC-30
Synonyms	University of Turku-Squamous Cell Carcinoma-30
Accession	CVCL_7834
Resource Identification Initiative	To cite this cell line use: UT-SCC-30 (RRID:CVCL_7834)
Comments	Omics: Array-based CGH. Omics: Transcriptome analysis by microarray. Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg282Pro (c.845G>C); ClinVar=VCV000376659; Zygosity=Homozygous (PubMed=8725545; PubMed=29970484).
Disease	Tongue squamous cell carcinoma (NCIt: C4648) Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	77Y
Category	Cancer cell line
Publications	PubMed=8725545; DOI=10.3109/00016489609137854 Pekkola-Heino K., Servomaa K., Kiuru A., Grenman R. Increased radiosensitivity is associated with p53 mutations in cell lines derived from oral cavity carcinoma. Acta Oto-Laryngol. 116:341-344(1996) PubMed=17312569; DOI=10.1002/hed.20478 Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y. Head and neck squamous cell carcinoma cell lines: established models and rationale for selection. Head Neck 29:163-188(2007) PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733 Lepikhova T., Karhemo P.-R., Louhimo R., Yadav B., Murumagi A., Kulesskiy E., Kivento M., Sihto H., Grenman R., Syrjanen S.M., Kallioniemi O.-P., Aittokallio T., Wennerberg K., Joensuu H., Monni O. Drug-sensitivity screening and genomic characterization of 45 HPV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy. Mol. Cancer Ther. 17:2060-2071(2018)
Encyclopedic resources	Wikidata; Q54992113
Gene expression databases	GEO; GSM2883367 GEO; GSM2888830
Polymorphism and mutation databases	IARC_TP53; 5105
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	13