Cellosaurus logo
expasy logo

Cellosaurus UT-SCC-26A (CVCL_7829)

[Text version]
Cell line name UT-SCC-26A
Synonyms University of Turku-Squamous Cell Carcinoma-26A
Accession CVCL_7829
Resource Identification Initiative To cite this cell line use: UT-SCC-26A (RRID:CVCL_7829)
Comments Derived from site: Metastatic; Cervical lymph node; UBERON=UBERON_0002429.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr236Ter (c.708C>A); Zygosity=Unspecified (PubMed=16203773).
Disease Hypopharyngeal squamous cell carcinoma (NCIt: C4043)
Squamous cell carcinoma of the hypopharynx (ORDO: Orphanet_494547)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_7830 ! UT-SCC-26B
Sex of cell Male
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=16035614; DOI=10.1007/s10585-004-6918-5
Mandic R., Ludwig T., Oberleithner H., Werner J.A.
Evaluation of head and neck squamous cell carcinoma invasiveness by the electrical resistance breakdown assay.
Clin. Exp. Metastasis 21:699-704(2004)

PubMed=16203773; DOI=10.1158/1078-0432.CCR-05-0378
Mandic R., Schamberger C.J., Muller J.F., Geyer M., Zhu L., Carey T.E., Grenman R., Dunne A.A., Werner J.A.
Reduced cisplatin sensitivity of head and neck squamous cell carcinoma cell lines correlates with mutations affecting the COOH-terminal nuclear localization signal of p53.
Clin. Cancer Res. 11:6845-6852(2005)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19414362
Mandic R., Rodgarkia-Dara C.J., Krohn V., Wiegand S., Grenman R., Werner J.A.
Cisplatin resistance of the HNSCC cell line UT-SCC-26A can be overcome by stimulation of the EGF-receptor.
Anticancer Res. 29:1181-1187(2009)

DOI=10.1158/1538-7445.AM2020-507
Kondratyev M.K., Pesic A., Dvorkin-Sheva A., Ketela T., Moffat J., Koritzinsky M., Wouters B.G.
Repurposing of FDA approved drugs for treatment of metastatic HNSCC.
Cancer Res. 80 Suppl. 16:507-507(2020)

Cross-references
Encyclopedic resources Wikidata; Q54992106
Polymorphism and mutation databases Cosmic; 1483465
IARC_TP53; 23611
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number12