ID   UT-SCC-19B
AC   CVCL_7817
SY   UTSCC19B; University of Turku-Squamous Cell Carcinoma-19B
DR   cancercelllines; CVCL_7817
DR   Wikidata; Q54992078
RX   DOI=10.1158/1538-7445.AM2020-507;
RX   PubMed=8782485;
RX   PubMed=15287027;
RX   PubMed=16715129;
RX   PubMed=17312569;
RX   PubMed=26694163;
RX   PubMed=30135316;
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Glu285Lys (c.853G>A); ClinVar=VCV000420133; Zygosity=Unspecified (PubMed=8782485; PubMed=15287027).
CC   Omics: Array-based CGH.
CC   Omics: Deep exome analysis.
CC   Omics: miRNA expression profiling.
CC   Derived from site: In situ; Larynx, glottis; UBERON=UBERON_0002486.
ST   Source(s): PubMed=30135316
ST   Amelogenin: X
ST   CSF1PO: 12
ST   D13S317: 11,13
ST   D16S539: 12
ST   D18S51: 16
ST   D19S433: 18.2
ST   D21S11: 32.2
ST   D2S1338: 19
ST   D3S1358: 15
ST   D5S818: 10,12
ST   D7S820: 12
ST   D8S1179: 10,14
ST   FGA: 24
ST   TH01: 6
ST   TPOX: 8
ST   vWA: 14,19
DI   NCIt; C4044; Laryngeal squamous cell carcinoma
DI   ORDO; Orphanet_494550; Squamous cell carcinoma of the larynx
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_7816 ! UT-SCC-19A
SX   Male
AG   44Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 16
//
RX   DOI=10.1158/1538-7445.AM2020-507;
RA   Kondratyev M.K., Pesic A., Dvorkin-Sheva A., Ketela T., Moffat J.,
RA   Koritzinsky M., Wouters B.G.;
RT   "Repurposing of FDA approved drugs for treatment of metastatic HNSCC.";
RL   Cancer Res. 80 Suppl. 16:507-507(2020).
//
RX   PubMed=8782485; DOI=10.1046/j.1365-2184.1996.01009.x;
RA   Servomaa K., Kiuru A., Grenman R., Pekkola-Heino K., Pulkkinen J.O.,
RA   Rytomaa T.;
RT   "p53 mutations associated with increased sensitivity to ionizing
RT   radiation in human head and neck cancer cell lines.";
RL   Cell Prolif. 29:219-230(1996).
//
RX   PubMed=15287027; DOI=10.1002/gcc.20066;
RA   Takebayashi S., Hickson A., Ogawa T., Jung K.-Y., Mineta H., Ueda Y.,
RA   Grenman R., Fisher S.G., Carey T.E.;
RT   "Loss of chromosome arm 18q with tumor progression in head and neck
RT   squamous cancer.";
RL   Genes Chromosomes Cancer 41:145-154(2004).
//
RX   PubMed=16715129; DOI=10.1038/sj.onc.1209690;
RA   Jarvinen A.-K., Autio R., Haapa-Paananen S., Wolf M., Saarela M.,
RA   Grenman R., Leivo I., Kallioniemi O.-P., Makitie A.A., Monni O.;
RT   "Identification of target genes in laryngeal squamous cell carcinoma
RT   by high-resolution copy number and gene expression microarray
RT   analyses.";
RL   Oncogene 25:6997-7008(2006).
//
RX   PubMed=17312569; DOI=10.1002/hed.20478;
RA   Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L.,
RA   Koch W.M., Ferris R.L., Lai S.Y.;
RT   "Head and neck squamous cell carcinoma cell lines: established models
RT   and rationale for selection.";
RL   Head Neck 29:163-188(2007).
//
RX   PubMed=26694163; DOI=10.1371/journal.pone.0144924; PMCID=PMC4692263;
RA   Janiszewska J., Szaumkessel M., Kostrzewska-Poczekaj M., Bednarek K.,
RA   Paczkowska J., Jackowska J., Grenman R., Szyfter K., Wierzbicka M.,
RA   Giefing M., Jarmuz-Szymczak M.;
RT   "Global miRNA expression profiling identifies miR-1290 as novel
RT   potential oncomiR in laryngeal carcinoma.";
RL   PLoS ONE 10:E0144924-E0144924(2015).
//
RX   PubMed=30135316; DOI=10.1172/jci.insight.122204; PMCID=PMC6141174;
RA   Jamieson S.M.F., Tsai P., Kondratyev M.K., Budhani P., Liu A.,
RA   Senzer N.N., Chiorean E.G., Jalal S.I., Nemunaitis J.J., Kee D.,
RA   Shome A., Wong W.W., Li D., Poonawala-Lohani N., Kakadia P.M.,
RA   Knowlton N.S., Lynch C.R.H., Hong C.R., Lee T.W., Grenman R.,
RA   Caporiccio L., McKee T.D., Zaidi M., Butt S., Macann A.M.J.,
RA   McIvor N.P., Chaplin J.M., Hicks K.O., Bohlander S.K., Wouters B.G.,
RA   Hart C.P., Print C.G., Wilson W.R., Curran M.A., Hunter F.W.;
RT   "Evofosfamide for the treatment of human papillomavirus-negative head
RT   and neck squamous cell carcinoma.";
RL   JCI Insight 3:e122204.1-e122204.19(2018).
//