• Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Met53Val (c.157A>G) (p.Asp67Gly, c.200A>G); ClinVar=VCV001467708; Zygosity=Homozygous (PubMed=18487078; PubMed=29970484).
  
• Mutation; HGNC; HGNC:11998; TP53; Simple; c.919+1G>C (IVS8+1G>C); ClinVar=VCV000428905; Zygosity=Heterozygous; Note=Splice donor mutation (PubMed=29970484).
  

PubMed=11799138; DOI=10.1177/002215540205000207
Eicheler W., Zips D., Dorfler A., Grenman R., Baumann M.
Splicing mutations in TP53 in human squamous cell carcinoma lines influence immunohistochemical detection.
J. Histochem. Cytochem. 50:197-204(2002)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=18487078; DOI=10.1016/j.oraloncology.2008.02.006
Hoffmann T.K., Sonkoly E., Hauser U., van Lierop A., Whiteside T.L., Klussmann J.P., Hafner D., Schuler P.J., Friebe-Hoffmann U., Scheckenbach K., Erjala K., Grenman R., Schipper J., Bier H., Balz V.
Alterations in the p53 pathway and their association with radio- and chemosensitivity in head and neck squamous cell carcinoma.
Oral Oncol. 44:1100-1109(2008)

PubMed=20429727; DOI=10.3109/02841861003614343
Sorensen B.S., Toustrup K., Horsman M.R., Overgaard J., Alsner J.
Identifying pH independent hypoxia induced genes in human squamous cell carcinomas in vitro.
Acta Oncol. 49:895-905(2010)

PubMed=29970484; DOI=10.1158/1535-7163.MCT-17-0733
Lepikhova T., Karhemo P.-R., Louhimo R., Yadav B., Murumagi A., Kulesskiy E., Kivento M., Sihto H., Grenman R., Syrjanen S.M., Kallioniemi O.-P., Aittokallio T., Wennerberg K., Joensuu H., Monni O.
Drug-sensitivity screening and genomic characterization of 45 HPV-negative head and neck carcinoma cell lines for novel biomarkers of drug efficacy.
Mol. Cancer Ther. 17:2060-2071(2018)