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Cellosaurus UM-SCC-92 (CVCL_7796)

[Text version]
Cell line name UM-SCC-92
Synonyms UMSCC-92; UMSCC92; University of Michigan-Squamous Cell Carcinoma-92
Accession CVCL_7796
Resource Identification Initiative To cite this cell line use: UM-SCC-92 (RRID:CVCL_7796)
Comments Population: Caucasian.
Omics: Genomics; Whole exome sequencing.
Omics: Variations; CNV analysis.
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_D2PH (UM-SCC-92 EGFR KO)
Sex of cell Female
Age at sampling 38Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX
D3S135815
D5S81811
D7S82011,12
D8S117910,13
D13S31712,14
D18S5114,15
D21S1129,31
FGA19,21
vWA17,20

Run an STR similarity search on this cell line
Publications

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R., Lyons R.H., Bradford C.R., Carey T.E.
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

PubMed=30527230; DOI=10.1016/j.oraloncology.2018.10.031; PMCID=PMC6349383
Ludwig M.L., Kulkarni A., Birkeland A.C., Michmerhuizen N.L., Foltin S.K., Mann J.E., Hoesli R.C., Devenport S.N., Jewell B.M., Shuman A.G., Spector M.E., Carey T.E., Jiang H., Brenner J.C.
The genomic landscape of UM-SCC oral cavity squamous cell carcinoma cell lines.
Oral Oncol. 87:144-151(2018)

PubMed=37844343; DOI=10.1016/j.archoralbio.2023.105822; PMCID=PMC11209876
Ludwig M.L., Michmerhuizen N.L., Wang J.-Y., Birkeland A.C., Majchrowski B.K., Nimmagadda S.V., Zhai J.-Y., Bhangale A., Kulkarni A., Jiang H., Swiecicki P.L., Brenner J.C.
Multi-kinase compensation rescues EGFR knockout in a cell line model of head and neck squamous cell carcinoma.
Arch. Oral Biol. 156:105822.1-105822.11(2023)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7796
Encyclopedic resources Wikidata; Q54990948
Gene expression databases GEO; GSM3631287
Polymorphism and mutation databases Progenetix; CVCL_7796
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number15