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Cellosaurus UM-SCC-8 (CVCL_7781)

[Text version]
Cell line name UM-SCC-8
Synonyms UMSCC-8; UMSCC8; SCC8; University of Michigan-Squamous Cell Carcinoma-8
Accession CVCL_7781
Resource Identification Initiative To cite this cell line use: UM-SCC-8 (RRID:CVCL_7781)
Comments Part of: MD Anderson Cell Lines Project.
Population: Caucasian.
Omics: CNV analysis.
Omics: Deep exome analysis.
Omics: Protein expression by reverse-phase protein arrays.
Derived from site: In situ; Oral cavity, alveolar ridge; UBERON=UBERON_0004102.
Disease Oral cavity squamous cell carcinoma (NCIt: C4833)
Squamous cell carcinoma of the oral cavity (ORDO: Orphanet_502363)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 76Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX
D3S135814,16
D5S81811,12
D7S82010,11
D8S117910,13
D13S31712
D18S5113,15
D21S1129,31.2
FGA22,23
vWA16

Run an STR similarity search on this cell line
Web pages https://tcpaportal.org/mclp/
Publications

PubMed=3855324; DOI=10.1288/00005537-198501000-00012
Baker S.R.
An in vivo model for squamous cell carcinoma of the head and neck.
Laryngoscope 95:43-56(1985)

PubMed=1851275; DOI=10.1177/019459989110400304
Bradford C.R., Zacks S.E., Androphy E.J., Gregoire L., Lancaster W.D., Carey T.E.
Human papillomavirus DNA sequences in cell lines derived from head and neck squamous cell carcinomas.
Otolaryngol. Head Neck Surg. 104:303-310(1991)

PubMed=1958593; DOI=10.1002/gcc.2870030406
Bradford C.R., Kimmel K.A., Van Dyke D.L., Worsham M.J., Tilley B.J., Burk D., del Rosario F., Lutz S., Tooley R., Hayashida D.J.S., Carey T.E.
11p deletions and breakpoints in squamous cell carcinoma: association with altered reactivity with the UM-E7 antibody.
Genes Chromosomes Cancer 3:272-282(1991)

DOI=10.1016/B978-0-12-333530-2.50007-1
Carey T.E.
Head and neck tumor cell lines.
(In) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York (1994)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198
Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R., Lyons R.H., Bradford C.R., Carey T.E.
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

PubMed=30527230; DOI=10.1016/j.oraloncology.2018.10.031
Ludwig M.L., Kulkarni A., Birkeland A.C., Michmerhuizen N.L., Foltin S.K., Mann J.E., Hoesli R.C., Devenport S.N., Jewell B.M., Shuman A.G., Spector M.E., Carey T.E., Jiang H., Brenner J.C.
The genomic landscape of UM-SCC oral cavity squamous cell carcinoma cell lines.
Oral Oncol. 87:144-151(2018)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7781
Encyclopedic resources Wikidata; Q54990921
Gene expression databases GEO; GSM3631263
Polymorphism and mutation databases Cosmic; 1130352
Cosmic; 2043898
Progenetix; CVCL_7781
Entry history
Entry creation04-Apr-2012
Last entry update30-Jan-2024
Version number20