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Cellosaurus UM-SCC-21A (CVCL_7730)

[Text version]
Cell line name UM-SCC-21A
Synonyms UMSCC-21A; UMSCC21A; University of Michigan-Squamous Cell Carcinoma-21A
Accession CVCL_7730
Resource Identification Initiative To cite this cell line use: UM-SCC-21A (RRID:CVCL_7730)
Disease Head and neck squamous cell carcinoma (NCIt: C34447)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_L143 ! UM-SCC-21B
Sex of cell Male
Age at sampling 64Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX,Y
D3S135815
D5S81811,12
D7S82010,11
D8S117913,14
D13S3178,9
D18S5114
D21S1129,32.2
FGA21
vWA16,18

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Publications

PubMed=3335022
Alley M.C., Scudiero D.A., Monks A., Hursey M.L., Czerwinski M.J., Fine D.L., Abbott B.J., Mayo J.G., Shoemaker R.H., Boyd M.R.
Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.
Cancer Res. 48:589-601(1988)

PubMed=1851275; DOI=10.1177/019459989110400304
Bradford C.R., Zacks S.E., Androphy E.J., Gregoire L., Lancaster W.D., Carey T.E.
Human papillomavirus DNA sequences in cell lines derived from head and neck squamous cell carcinomas.
Otolaryngol. Head Neck Surg. 104:303-310(1991)

PubMed=1958593; DOI=10.1002/gcc.2870030406
Bradford C.R., Kimmel K.A., Van Dyke D.L., Worsham M.J., Tilley B.J., Burk D., del Rosario F., Lutz S., Tooley R., Hayashida D.J.S., Carey T.E.
11p deletions and breakpoints in squamous cell carcinoma: association with altered reactivity with the UM-E7 antibody.
Genes Chromosomes Cancer 3:272-282(1991)

PubMed=15287027; DOI=10.1002/gcc.20066
Takebayashi S., Hickson A., Ogawa T., Jung K.-Y., Mineta H., Ueda Y., Grenman R., Fisher S.G., Carey T.E.
Loss of chromosome arm 18q with tumor progression in head and neck squamous cancer.
Genes Chromosomes Cancer 41:145-154(2004)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R., Lyons R.H., Bradford C.R., Carey T.E.
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

Cross-references
Anatomy/cell type resources BTO; BTO:0002713
Encyclopedic resources Wikidata; Q54990835
Entry history
Entry creation04-Apr-2012
Last entry update21-Mar-2023
Version number14