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Cellosaurus UM-SCC-20 (CVCL_7729)

[Text version]
Cell line name UM-SCC-20
Synonyms UMSCC-20; UMSCC20; University of Michigan-Squamous Cell Carcinoma-20
Accession CVCL_7729
Resource Identification Initiative To cite this cell line use: UM-SCC-20 (RRID:CVCL_7729)
Comments Derived from site: Metastatic; Neck; UBERON=UBERON_0000974.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro71_Pro72del (c.211_216del6); Zygosity=Unspecified (PubMed=12884349).
Disease Laryngeal squamous cell carcinoma (NCIt: C4044)
Squamous cell carcinoma of the larynx (ORDO: Orphanet_494550)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 67Y
Category Cancer cell line
STR profile Source(s): PubMed=19760794

Markers:
AmelogeninX,Y
D3S135814,15
D5S81811,12
D7S8209,10
D8S117912,15
D13S3178,10
D18S5113,15
D21S1128,30.2
FGA18,22.2
vWA16,18

Run an STR similarity search on this cell line
Publications

DOI=10.1016/B978-0-12-333530-2.50007-1
Carey T.E.
Head and neck tumor cell lines.
(In book chapter) Atlas of human tumor cell lines; Hay R.J., Park J.-G., Gazdar A.F. (eds.); pp.79-120; Academic Press; New York; USA (1994)

PubMed=12884349; DOI=10.1002/hed.10274
Bradford C.R., Zhu S.-B., Ogawa H., Ogawa T., Ubell M., Narayan A., Johnson G., Wolf G.T., Fisher S.G., Carey T.E.
p53 mutation correlates with cisplatin sensitivity in head and neck squamous cell carcinoma lines.
Head Neck 25:654-661(2003)

PubMed=17312569; DOI=10.1002/hed.20478
Lin C.J., Grandis J.R., Carey T.E., Gollin S.M., Whiteside T.L., Koch W.M., Ferris R.L., Lai S.Y.
Head and neck squamous cell carcinoma cell lines: established models and rationale for selection.
Head Neck 29:163-188(2007)

PubMed=19760794; DOI=10.1002/hed.21198; PMCID=PMC3292176
Brenner J.C., Graham M.P., Kumar B., Saunders L.M., Kupfer R., Lyons R.H., Bradford C.R., Carey T.E.
Genotyping of 73 UM-SCC head and neck squamous cell carcinoma cell lines.
Head Neck 32:417-426(2010)

Cross-references
Encyclopedic resources Wikidata; Q54990834
Polymorphism and mutation databases IARC_TP53; 18880
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number18