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Cellosaurus PR-GTL-16 (CVCL_7696)

[Text version]
Cell line name PR-GTL-16
Accession CVCL_7696
Resource Identification Initiative To cite this cell line use: PR-GTL-16 (RRID:CVCL_7696)
Comments Population: Japanese.
Selected for resistance to: ChEBI; CHEBI_90197; PHA-665752.
Derived from site: Metastatic; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg110Cys (c.328C>T); ClinVar=VCV000142206; Zygosity=Heterozygous (from parent cell line).
Disease Gastric adenocarcinoma (NCIt: C4004)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_7668 (GTL-16)
Sex of cell Female
Age at sampling 62Y
Category Cancer cell line
Publications

PubMed=21208906; DOI=10.1158/1078-0432.CCR-10-0253; PMCID=PMC3263825
Bachleitner-Hofmann T., Sun M.Y., Chen C.-T., Liska D., Zeng Z.-S., Viale A.J., Olshen A.B., Mittlbock M., Christensen J.G., Rosen N., Solit D.B., Weiser M.R.
Antitumor activity of SNX-2112, a synthetic heat shock protein-90 inhibitor, in MET-amplified tumor cells with or without resistance to selective MET Inhibition.
Clin. Cancer Res. 17:122-133(2011)

Cross-references
Cell line databases/resources cancercelllines; CVCL_7696
Encyclopedic resources Wikidata; Q54947819
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number19