ID   MZ-MEL-3.1
AC   CVCL_7689
SY   MZ-Mel-3.1; MZ-Mel-3; MzMel3
DR   cancercelllines; CVCL_7689
DR   Cosmic; 2163796
DR   ESTDAB; ESTDAB-055
DR   Wikidata; Q54907224
RX   PubMed=8375931;
RX   PubMed=15592718;
RX   PubMed=23851445;
CC   HLA typing: A*26:01,26:01; B*18:01,18:01; C*07:01:01,07:01:01; DPB1*04:01; DQB1*06:02,03:01:01; DRB1*11:01,15:01 (PubMed=15592718).
CC   Sequence variation: Mutation; HGNC; HGNC:1097; BRAF; Simple; p.Val600Glu (c.1799T>A); ClinVar=VCV000013961; Zygosity=Unspecified (PubMed=23851445).
ST   Source(s): ESTDAB=ESTDAB-055
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D13S317: 11,12
ST   D3S1358: 15,17
ST   D5S818: 9,11
ST   D7S820: 9
ST   FGA: 20,23
ST   TH01: 6,8
ST   TPOX: 8,11
ST   vWA: 14,17
DI   NCIt; C3224; Melanoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 19
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RX   PubMed=8375931; DOI=10.1002/ijc.2910550324;
RA   Bernhard H., Karbach J., Strittmatter W.,
RA   Meyer zum Buschenfelde K.-H., Knuth A.;
RT   "Induction of tumor-cell lysis by bi-specific antibody recognizing
RT   ganglioside GD2 and T-cell antigen CD3.";
RL   Int. J. Cancer 55:465-470(1993).
//
RX   PubMed=15592718; DOI=10.1007/s00262-004-0561-5; PMCID=PMC11032966;
RA   Rodriguez T., Mendez R., Roberts C.H., Ruiz-Cabello Osuna F., Dodi I.A.,
RA   Lopez-Nevot M.A., Paco L., Maleno I., Marsh S.G.E., Pawelec G.,
RA   Garrido F.;
RT   "High frequency of homozygosity of the HLA region in melanoma cell
RT   lines reveals a pattern compatible with extensive loss of
RT   heterozygosity.";
RL   Cancer Immunol. Immunother. 54:141-148(2005).
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RX   PubMed=23851445; DOI=10.1158/1541-7786.MCR-13-0006;
RA   Dahl C., Christensen C., Jonsson G., Lorentzen A., Skjodt M.L.,
RA   Borg A., Pawelec G., Guldberg P.;
RT   "Mutual exclusivity analysis of genetic and epigenetic drivers in
RT   melanoma identifies a link between p14 ARF and RARbeta signaling.";
RL   Mol. Cancer Res. 11:1166-1178(2013).
//