Cellosaurus logo
expasy logo

Cellosaurus GD25 (CVCL_7264)

[Text version]
Cell line name GD25
Accession CVCL_7264
Resource Identification Initiative To cite this cell line use: GD25 (RRID:CVCL_7264)
Comments Knockout cell: Method=Gene trap; MGI; MGI:96610; Itgb1.
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: 129S2/SvPas.
Hierarchy Parent: CVCL_E078 (G-201)
Children:
CVCL_GR75 (GD25T)
Sex of cell Male
Age at sampling Blastocyst stage
Category Transformed cell line
Web pages https://web.archive.org/web/20160325165513/http://bioinfoweb.com/CLDB-GD25.htm
Publications

PubMed=7533171; DOI=10.1083/jcb.128.5.979; PMCID=PMC2120384
Fassler R., Pfaff M., Murphy J., Noegel A.A., Johansson S., Timpl R., Albrecht R.
Lack of beta 1 integrin gene in embryonic stem cells affects morphology, adhesion, and migration but not integration into the inner cell mass of blastocysts.
J. Cell Biol. 128:979-988(1995)

PubMed=8567726; DOI=10.1083/jcb.132.1.227; PMCID=PMC2120698
Wennerberg K., Lohikangas L., Gullberg E.D., Pfaff M., Johansson S., Fassler R.
Beta 1 integrin-dependent and -independent polymerization of fibronectin.
J. Cell Biol. 132:227-238(1996)

PubMed=10574722; DOI=10.1242/jcs.112.24.4751
Svineng G., Johansson S.
Integrin subunits (beta)1C-1 and (beta)1C-2 expressed in GD25T cells are retained and degraded intracellularly rather than localised to the cell surface.
J. Cell Sci. 112:4751-4761(1999)

PubMed=10601344; DOI=10.1083/jcb.147.6.1325; PMCID=PMC2168093
Gimond C., van der Flier A., van Delft S., Brakebusch C., Kuikman I., Collard J.G., Fassler R., Sonnenberg A.
Induction of cell scattering by expression of beta1 integrins in beta1-deficient epithelial cells requires activation of members of the rho family of GTPases and downregulation of cadherin and catenin function.
J. Cell Biol. 147:1325-1340(1999)

Cross-references
Encyclopedic resources Wikidata; Q54835527
Experimental variables resources EFO; EFO_0022803
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number13