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Cellosaurus CT26.WT (CVCL_7256)

[Text version]
Cell line name CT26.WT
Synonyms CT-26 WT; CT26.wt; CT26WT
Accession CVCL_7256
Resource Identification Initiative To cite this cell line use: CT26.WT (RRID:CVCL_7256)
Comments Transformant: ChEBI; CHEBI_82373; N-nitroso-N-methylurethane (NNMU).
Omics: Array-based CGH.
Omics: Deep exome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
  • Gene deletion; MGI; MGI:104738; Cdkn2a; Zygosity=Homozygous (PubMed=24621249).
  • Mutation; MGI; MGI:96680; Kras; Simple; p.Gly12Asp (c.35G>A); Zygosity=Homozygous (PubMed=24621249).
Disease Mouse colon adenocarcinoma (NCIt: C120044)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: BALB/c.
Hierarchy Parent: CVCL_7254 (CT26)
Children:
CVCL_9V16 (CT26-DsRed)CVCL_7255 (CT26.CL25)CVCL_UE29 (CT26.WT human B7H4)
CVCL_XZ50 (CT26.WT human CLDN18.2)CVCL_QZ99 (CT26.WT-eGFP-Puro)CVCL_RA00 (CT26.WT-Fluc-Neo)
CVCL_RA01 (CT26.WT-Fluc-Neo/eGFP-Puro)CVCL_RA02 (CT26.WT-Fluc-Neo/iRFP-Puro)CVCL_RA03 (CT26.WT-iRFP-Neo)
CVCL_RA04 (CT26.WT-iRFP-Neo/mNIS-Puro)CVCL_C8XR (CT26.WT-Luc)CVCL_RA05 (CT26.WT-mNIS (monoclonal))
CVCL_RA06 (CT26.WT-mNIS-Neo/eGFP-Puro)CVCL_RA07 (CT26.WT-mNIS-Neo/Fluc-Puro)CVCL_RA08 (CT26.WT-mNIS-Puro)
CVCL_0A66 (LM17)CVCL_D8FR (Ubigene CT26.WT Ddr1 KO)CVCL_D8FS (Ubigene CT26.WT Ecm1 KO)
CVCL_D8FT (Ubigene CT26.WT Il1r1 KO)CVCL_D8FU (Ubigene CT26.WT Lrpprc KO)CVCL_D8FV (Ubigene CT26.WT Stat3 KO)
CVCL_D8FW (Ubigene CT26.WT Tead1 KO)CVCL_D8FX (Ubigene CT26.WT Tead4 KO)CVCL_D8FY (Ubigene CT26.WT Tnfrsf1b KO)
CVCL_D8FZ (Ubigene CT26.WT Zc3h3 KO)
Sex of cell Female
Category Cancer cell line
STR profile Source(s): PubMed=31220119; Ubigene=YC-B003

Markers:
Mouse STR 1-114,15
Mouse STR 1-217,18
Mouse STR 2-116,17
Mouse STR 3-214
Mouse STR 4-221.3
Mouse STR 5-514
Mouse STR 6-418,20
Mouse STR 6-712
Mouse STR 7-125.2
Mouse STR 8-113
Mouse STR 11-217
Mouse STR 12-116,17
Mouse STR 13-116.2,17.2,18.2
Mouse STR 15-321.3,22.3
Mouse STR 17-215,16,17
Mouse STR 18-319,20
Mouse STR 19-213
Mouse STR X-125,26

Run an STR similarity search on this cell line
Publications

PubMed=7722321; DOI=10.4049/jimmunol.154.9.4685; PMCID=PMC1976248
Wang M., Bronte V., Chen P.W., Gritz L., Panicali D., Rosenberg S.A., Restifo N.P.
Active immunotherapy of cancer with a nonreplicating recombinant fowlpox virus encoding a model tumor-associated antigen.
J. Immunol. 154:4685-4692(1995)

PubMed=11089883; DOI=10.1023/A:1006730320248
Ikubo A., Aoki Y., Nagai E., Suzuki T.
Highly metastatic variant of a mouse colon carcinoma cell line, LM17 and its response to GM-CSF gene therapy.
Clin. Exp. Metastasis 17:849-855(1999)

PubMed=24621249; DOI=10.1186/1471-2164-15-190; PMCID=PMC4007559
Castle J.C., Loewer M., Boegel S., de Graaf J., Bender C., Tadmor A.D., Boisguerin V., Bukur T., Sorn P., Paret C., Diken M., Kreiter S., Tureci O., Sahin U.
Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma.
BMC Genomics 15:190.1-190.12(2014)

PubMed=25277546; DOI=10.1186/1471-2164-15-847; PMCID=PMC4198738
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. 3rd, Pardo-Manuel de Villena F.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

DOI=10.21926/obm.genet.1803037
Rhode H., Liehr T., Kosyakova N., Rincic M., Hussein Azawi S.S.
Molecular cytogenetic characterization of two murine colorectal cancer cell lines.
OBM Genetics 2:1803037.1-1803037.24(2018)

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cross-references
Cell line collections (Providers) ATCC; CRL-2638
BCRC; 60447
BCRJ; 0402
CLS; 305178
Ubigene; YC-B003
Cell line databases/resources CLO; CLO_0002631
CCRID; 1101MOU-PUMC000275
CCRID; 3101MOUTCM37
Anatomy/cell type resources BTO; BTO_0006018
Biological sample resources BioSample; SAMN11397649
Chemistry resources ChEMBL-Cells; CHEMBL4513106
ChEMBL-Targets; CHEMBL4513123
PubChem_Cell_line; CVCL_7256
Encyclopedic resources Wikidata; Q54814710
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17