ID   Rael
AC   CVCL_7208
SY   Rael-BL; RAEL
DR   Cosmic; 931109
DR   Cosmic; 2361385
DR   NCBI_Iran; C186
DR   Wikidata; Q54949130
RX   PubMed=3026973;
RX   PubMed=4122458;
RX   PubMed=4347031;
RX   PubMed=4364259;
RX   PubMed=6231253;
RX   PubMed=6811418;
RX   PubMed=7316467;
RX   PubMed=8547074;
RX   PubMed=9473234;
RX   PubMed=16051863;
RX   PubMed=24590883;
RX   PubMed=28960205;
CC   Population: African; Kenyan.
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 02-05-24; Version: 15
//
RX   PubMed=3026973; DOI=10.1002/ijc.2910390215;
RA   Ehlin-Henriksson B., Manneborg-Sandlund A., Klein G.;
RT   "Expression of B-cell-specific markers in different Burkitt lymphoma
RT   subgroups.";
RL   Int. J. Cancer 39:211-218(1987).
//
RX   PubMed=4122458; DOI=10.1002/ijc.2910100108;
RA   Klein G., Dombos L., Gothoskar B.;
RT   "Sensitivity of Epstein-Barr virus (EBV) producer and non-producer
RT   human lymphoblastoid cell lines to superinfection with EB-virus.";
RL   Int. J. Cancer 10:44-57(1972).
//
RX   PubMed=4347031; DOI=10.1093/jnci/48.1.87;
RA   Hewetson J.F., Gothoskar B., Klein G.;
RT   "Radioiodine-labeled antibody test for the detection of membrane
RT   antigens associated with Epstein-Barr virus.";
RL   J. Natl. Cancer Inst. 48:87-94(1972).
//
RX   PubMed=4364259; DOI=10.1002/ijc.2910110210;
RA   Klein G., Dombos L.;
RT   "Relationship between the sensitivity of EBV-carrying lymphoblastoid
RT   lines to superinfection and the inducibility of the resident viral
RT   genome.";
RL   Int. J. Cancer 11:327-337(1973).
//
RX   PubMed=6231253; DOI=10.1002/ijc.2910330407;
RA   Ehlin-Henriksson B., Klein G.;
RT   "Distinction between Burkitt lymphoma subgroups by monoclonal
RT   antibodies: relationships between antigen expression and type of
RT   chromosomal translocation.";
RL   Int. J. Cancer 33:459-463(1984).
//
RX   PubMed=6811418; DOI=10.1016/S0171-2985(11)80031-8;
RA   Spira G., Koide N., Aman P., Ber R., Klein G.;
RT   "Truncated mu chain in a Burkitt lymphoma line (P3HR-1) and its fate
RT   in various hemapoietic somatic cell hybrids.";
RL   Immunobiology 162:199-209(1982).
//
RX   PubMed=7316467; DOI=10.1111/j.1469-1809.1980.tb00953.x;
RA   Povey S., Jeremiah S., Arthur E., Steel M., Klein G.;
RT   "Differences in genetic stability between human cell lines from
RT   patients with and without lymphoreticular malignancy.";
RL   Ann. Hum. Genet. 44:119-133(1980).
//
RX   PubMed=8547074; DOI=10.1111/j.1365-2141.1995.tb05302.x;
RA   Siebert R., Willers C.P., Schramm A., Fossa A., Dresen I.M.G.,
RA   Uppenkamp M.J., Nowrousian M.R., Seeber S., Opalka B.;
RT   "Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and
RT   lymphoblastic leukaemia cell lines.";
RL   Br. J. Haematol. 91:350-354(1995).
//
RX   PubMed=9473234; DOI=10.1182/blood.V91.5.1680;
RA   Klangby U., Okan I., Magnusson K.P., Wendland M., Lind P., Wiman K.G.;
RT   "p16/INK4a and p15/INK4b gene methylation and absence of p16/INK4a
RT   mRNA and protein expression in Burkitt's lymphoma.";
RL   Blood 91:1680-1687(1998).
//
RX   PubMed=16051863; DOI=10.1128/JVI.79.16.10709-10717.2005; PMCID=PMC1182620;
RA   Kelly G.L., Milner A.E., Tierney R.J., Croom-Carter D.S.G.,
RA   Altmann M., Hammerschmidt W., Bell A.I., Rickinson A.B.;
RT   "Epstein-Barr virus nuclear antigen 2 (EBNA2) gene deletion is
RT   consistently linked with EBNA3A, -3B, and -3C expression in Burkitt's
RT   lymphoma cells and with increased resistance to apoptosis.";
RL   J. Virol. 79:10709-10717(2005).
//
RX   PubMed=24590883; DOI=10.1002/gcc.22161;
RA   Murga Penas E.-M., Schilling G., Behrmann P., Klokow M.,
RA   Vettorazzi E., Bokemeyer C., Dierlamm J.;
RT   "Comprehensive cytogenetic and molecular cytogenetic analysis of 44
RT   Burkitt lymphoma cell lines: secondary chromosomal changes
RT   characterization, karyotypic evolution, and comparison with primary
RT   samples.";
RL   Genes Chromosomes Cancer 53:497-515(2014).
//
RX   PubMed=28960205; DOI=10.1038/cdd.2017.150; PMCID=PMC5762840;
RA   Fitzsimmons L., Boyce A.J., Wei W.-B., Chang C., Croom-Carter D.S.G.,
RA   Tierney R.J., Herold M.J., Bell A.I., Strasser A., Kelly G.L.,
RA   Rowe M.;
RT   "Coordinated repression of BIM and PUMA by Epstein-Barr virus latent
RT   genes maintains the survival of Burkitt lymphoma cells.";
RL   Cell Death Differ. 25:241-254(2018).
//