ID   Mwika
AC   CVCL_7205
SY   MWIKA; Mwi-BL; MWI-BL; MWI; Mwi
DR   cancercelllines; CVCL_7205
DR   Cosmic; 2804850
DR   Wikidata; Q54907132
RX   PubMed=2470097;
RX   PubMed=2824665;
RX   PubMed=2943927;
RX   PubMed=3035497;
RX   PubMed=8108117;
RX   PubMed=9882297;
CC   Population: African; Kenyan.
CC   Sequence variation: Mutation; HGNC; HGNC:7553; MYC; Simple; p.Pro72Ser (c.214C>T); ClinVar=VCV000012574; Zygosity=Unspecified (PubMed=8108117).
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Cell type: B-cell; CL=CL_0000236.
DI   NCIt; C27694; EBV-related Burkitt lymphoma
DI   ORDO; Orphanet_543; Burkitt lymphoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   4Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 17
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RX   PubMed=2470097; DOI=10.1073/pnas.86.9.3257; PMCID=PMC287109;
RA   Shtivelman E., Henglein B., Groitl P., Lipp M., Bishop J.M.;
RT   "Identification of a human transcription unit affected by the variant
RT   chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:3257-3260(1989).
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RX   PubMed=2824665; DOI=10.1099/0022-1317-68-11-2853;
RA   Young L.S., Yao Q.-Y., Rooney C.M., Sculley T.B., Moss D.J., Rupani H.,
RA   Laux G., Bornkamm G.-W., Rickinson A.B.;
RT   "New type B isolates of Epstein-Barr virus from Burkitt's lymphoma and
RT   from normal individuals in endemic areas.";
RL   J. Gen. Virol. 68:2853-2862(1987).
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RX   PubMed=2943927; DOI=10.1093/jnci/77.3.681;
RA   Rooney C.M., Gregory C.D., Rowe M., Finerty S., Edwards C.F., Rupani H.,
RA   Rickinson A.B.;
RT   "Endemic Burkitt's lymphoma: phenotypic analysis of tumor biopsy cells
RT   and of derived tumor cell lines.";
RL   J. Natl. Cancer Inst. 77:681-687(1986).
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RX   PubMed=3035497; DOI=10.1093/nar/15.11.4553; PMCID=PMC340879;
RA   Szajnert M.-F., Saule S., Bornkamm G.-W., Wajcman H., Lenoir G.M.,
RA   Kaplan J.-C.;
RT   "Clustered somatic mutations in and around first exon of
RT   non-rearranged c-myc in Burkitt lymphoma with t(8;22) translocation.";
RL   Nucleic Acids Res. 15:4553-4565(1987).
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RX   PubMed=8108117;
RA   Albert T., Urlbauer B., Kohlhuber F., Hammersen B., Eick D.;
RT   "Ongoing mutations in the N-terminal domain of c-Myc affect
RT   transactivation in Burkitt's lymphoma cell lines.";
RL   Oncogene 9:759-763(1994).
//
RX   PubMed=9882297; DOI=10.1128/JVI.73.2.965-975.1999; PMCID=PMC103916;
RA   Habeshaw G., Yao Q.-Y., Bell A.I., Morton D., Rickinson A.B.;
RT   "Epstein-Barr virus nuclear antigen 1 sequences in endemic and
RT   sporadic Burkitt's lymphoma reflect virus strains prevalent in
RT   different geographic areas.";
RL   J. Virol. 73:965-975(1999).
//