ID   SCMC-ES2
AC   CVCL_7124
SY   SCMC-ES-2; Saitama Children's Medical Center-Ewing Sarcoma 2
DR   cancercelllines; CVCL_7124
DR   Cosmic; 1078361
DR   Cosmic; 1381108
DR   IARC_TP53; 1274
DR   JCRB; NIHS0049
DR   Wikidata; Q54952451
RX   CelloPub=CLPUB00110;
RX   DOI=10.2198/sbk.34.289;
RX   PubMed=7591257;
RX   PubMed=8221663;
CC   Population: Japanese.
CC   Sequence variation: Gene fusion; HGNC; HGNC:3446; ERG + HGNC; HGNC:3508; EWSR1; Name(s)=EWSR1-ERG, EWS-ERG (PubMed=7591257).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Cys176Phe (c.527G>T); ClinVar=VCV000376569; Zygosity=Unspecified (PubMed=8221663).
CC   Discontinued: JCRB; NIHS0049; true.
DI   NCIt; C4817; Ewing sarcoma
DI   ORDO; Orphanet_319; Ewing sarcoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   8Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 20
//
RX   CelloPub=CLPUB00110;
RA   Hayashi Y., Hanada R., Moriwaki K., Yamamoto K., Imaizumi S.,
RA   Hirata A., Nishida T.;
RT   "Establishment and characterization of cell lines derived from
RT   malignant tumors in children.";
RL   Saitama Shoni Iryo Senta Igaku-shi 8:16-23(1991).
//
RX   DOI=10.2198/sbk.34.289;
RA   Mizusawa H.;
RT   "Operation of the JCRB cell bank and isoenzyme.";
RL   Seibutsu Butsuri Kagaku 34:289-292(1990).
//
RX   PubMed=7591257; DOI=10.1002/ijc.2910630407;
RA   Ida K., Kobayashi S., Taki T., Hanada R., Bessho F., Yamamori S.,
RA   Sugimoto T., Ohki M., Hayashi Y.;
RT   "EWS-FLI-1 and EWS-ERG chimeric mRNAs in Ewing's sarcoma and primitive
RT   neuroectodermal tumor.";
RL   Int. J. Cancer 63:500-504(1995).
//
RX   PubMed=8221663;
RA   Komuro H., Hayashi Y., Kawamura M., Hayashi K., Kaneko Y.,
RA   Kamoshita S., Hanada R., Yamamoto K., Hongo T., Yamada M., Tsuchida Y.;
RT   "Mutations of the p53 gene are involved in Ewing's sarcomas but not in
RT   neuroblastomas.";
RL   Cancer Res. 53:5284-5288(1993).
//