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Cellosaurus POGRS-1 (CVCL_7111)

[Text version]
Cell line name POGRS-1
Synonyms PO-GRS1; P0-GRS1; POGRS1
Accession CVCL_7111
Secondary accession CVCL_6710
Resource Identification Initiative To cite this cell line use: POGRS-1 (RRID:CVCL_7111)
Comments Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:5173; HRAS (Note=With p.Gly12Val).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Ovary, ovarian follicle, granulosa cell layer; UBERON=UBERON_0005170.
Cell type: Granulosa cell; CL=CL_0000501.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Sex of cell Female
Age at sampling 25D
Category Transformed cell line
Publications

PubMed=2170421; DOI=10.1083/jcb.111.4.1373; PMCID=PMC2116250
Hanukoglu I., Suh B.-S., Himmelhoch S., Amsterdam A.
Induction and mitochondrial localization of cytochrome P450scc system enzymes in normal and transformed ovarian granulosa cells.
J. Cell Biol. 111:1373-1381(1990)

PubMed=2171916; DOI=10.1210/endo-127-5-2489
Suh B.-S., Amsterdam A.
Establishment of highly steroidogenic granulosa cell lines by cotransfection with SV40 and Ha-ras oncogene: induction of steroidogenesis by cyclic adenosine 3'-5'-monophosphate and its suppression by phorbol ester.
Endocrinology 127:2489-2500(1990)

PubMed=8961254; DOI=10.1016/S0303-7207(96)03916-0
Selvaraj N., Israeli D., Amsterdam A.
Partial sequencing of the rat steroidogenic acute regulatory protein message from immortalized granulosa cells: regulation by gonadotropins and isoproterenol.
Mol. Cell. Endocrinol. 123:171-177(1996)

PubMed=15541573; DOI=10.1016/j.mce.2004.04.018
Havelock J.C., Rainey W.E., Carr B.R.
Ovarian granulosa cell lines.
Mol. Cell. Endocrinol. 228:67-78(2004)

Cross-references
Anatomy/cell type resources BTO; BTO_0002287
Encyclopedic resources Wikidata; Q54947706
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number14