Cellosaurus cell line MR-Mel (CVCL

Cross-references
Cell line name	MR-Mel
Accession	CVCL_7081
Resource Identification Initiative	To cite this cell line use: MR-Mel (RRID:CVCL_7081)
Comments	Derived from site: Metastatic; Not specified.
Sequence variations	Gene deletion; HGNC; HGNC:583; APC; Zygosity=Homozygous (PubMed=18384130). Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Gln939Ter (c.2815C>T); ClinVar=VCV000089318; Zygosity=Unspecified (PubMed=18384130). Mutation; HGNC; HGNC:7329; MSH6; Simple; p.Thr1008Ile (c.3023C>T); ClinVar=VCV000569009; Zygosity=Unspecified (PubMed=18384130).
Disease	Melanoma (NCIt: C3224)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Category	Cancer cell line
Publications	PubMed=18384130; DOI=10.1002/gcc.20567 Castiglia D., Bernardini S., Alvino E., Pagani E., De Luca N., Falcinelli S., Pacchiarotti A., Bonmassar E., Zambruno G., D'Atri S. Concomitant activation of Wnt pathway and loss of mismatch repair function in human melanoma. Genes Chromosomes Cancer 47:614-624(2008)
Anatomy/cell type resources	BTO; BTO_0003790
Encyclopedic resources	Wikidata; Q54906566
Polymorphism and mutation databases	Cosmic; 1109799
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	9