ID   GIST62
AC   CVCL_7043
SY   GIST-62; GIST 62
DR   cancercelllines; CVCL_7043
DR   Cosmic; 1180675
DR   GEO; GSM486230
DR   Progenetix; CVCL_7043
DR   Wikidata; Q54835861
RX   PubMed=16982758;
RX   PubMed=19706776;
RX   PubMed=30488756;
CC   Sequence variation: Mutation; HGNC; HGNC:6342; KIT; Unexplicit; Ex11del; Zygosity=Unspecified (PubMed=16982758; PubMed=19706776).
CC   Cell type: Interstitial cell of Cajal; CL=CL_0002088.
DI   NCIt; C3868; Gastrointestinal stromal tumor
DI   ORDO; Orphanet_44890; Gastrointestinal stromal tumor
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 15
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RX   PubMed=16982758; DOI=10.1158/0008-5472.CAN-06-0165;
RA   Bauer S., Yu L.K., Demetri G.D., Fletcher J.A.;
RT   "Heat shock protein 90 inhibition in imatinib-resistant
RT   gastrointestinal stromal tumor.";
RL   Cancer Res. 66:9153-9161(2006).
//
RX   PubMed=19706776; DOI=10.1158/0008-5472.CAN-08-4004; PMCID=PMC2905726;
RA   Muhlenberg T., Zhang Y.-X., Wagner A.J., Grabellus F., Bradner J.E.,
RA   Taeger G., Lang H., Taguchi T., Schuler M., Fletcher J.A., Bauer S.;
RT   "Inhibitors of deacetylases suppress oncogenic KIT signaling,
RT   acetylate HSP90, and induce apoptosis in gastrointestinal stromal
RT   tumors.";
RL   Cancer Res. 69:6941-6950(2009).
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RX   PubMed=30488756; DOI=10.1080/15384101.2018.1553335; PMCID=PMC6300111;
RA   Tu Y.-Q., Zuo R., Ni N., Eilers G., Wu D.-L., Pei Y.-T., Nie Z.-M.,
RA   Wu Y.-Q., Wu Y.-H., Ou W.-B.;
RT   "Activated tyrosine kinases in gastrointestinal stromal tumor with
RT   loss of KIT oncoprotein expression.";
RL   Cell Cycle 17:2577-2592(2018).
//