ID   ACC-LC-48
AC   CVCL_7018
SY   OT1; SCLC-OT1; Aichi Cancer Center-Lung Cancer-48
DR   cancercelllines; CVCL_7018
DR   Cosmic; 934417
DR   Cosmic; 1089234
DR   IARC_TP53; 18795
DR   Wikidata; Q54608193
RX   PubMed=1710138;
RX   PubMed=2540905;
RX   PubMed=7834619;
RX   PubMed=8384671;
RX   PubMed=8385084;
RX   PubMed=12794755;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg249Ser (c.747G>T); ClinVar=VCV000012352; Zygosity=Unspecified (PubMed=12794755).
CC   Derived from site: Metastatic; Pericardial effusion; UBERON=UBERON_0002409.
DI   NCIt; C4917; Lung small cell carcinoma
DI   ORDO; Orphanet_70573; Small cell lung cancer
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_7021 ! ACC-LC-52
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 18
//
RX   PubMed=1710138; PMCID=PMC2204105;
RA   Hida T., Koike K., Sekido Y., Nishida K., Sugiura T., Ariyoshi Y.,
RA   Takahashi T., Ueda R.;
RT   "Epitope analysis of cluster 1 and NK cell-related monoclonal
RT   antibodies.";
RL   Br. J. Cancer Suppl. 14:24-28(1991).
//
RX   PubMed=2540905;
RA   Takahashi T., Obata Y., Sekido Y., Hida T., Ueda R., Watanabe H.,
RA   Ariyoshi Y., Sugiura T., Takahashi T.;
RT   "Expression and amplification of myc gene family in small cell lung
RT   cancer and its relation to biological characteristics.";
RL   Cancer Res. 49:2683-2688(1989).
//
RX   PubMed=7834619;
RA   Washimi O., Nagatake M., Osada H., Ueda R., Koshikawa T., Seki T.,
RA   Takahashi T., Takahashi T.;
RT   "In vivo occurrence of p16 (MTS1) and p15 (MTS2) alterations
RT   preferentially in non-small cell lung cancers.";
RL   Cancer Res. 55:514-517(1995).
//
RX   PubMed=8384671; DOI=10.1093/oxfordjournals.jjco.a039602;
RA   Hida T., Ariyoshi Y., Kuwabara M., Sugiura T., Takahashi T.,
RA   Takahashi T., Hosoda K., Niitsu Y., Ueda R.;
RT   "Glutathione S-transferase pi levels in a panel of lung cancer cell
RT   lines and its relation to chemo-radiosensitivity.";
RL   Jpn. J. Clin. Oncol. 23:14-19(1993).
//
RX   PubMed=8385084; DOI=10.1111/j.1349-7006.1993.tb02851.x; PMCID=PMC5919128;
RA   Suzuki S., Takahashi T., Nakamura S., Koike K., Ariyoshi Y.,
RA   Takahashi T., Ueda R.;
RT   "Alterations of integrin expression in human lung cancer.";
RL   Jpn. J. Cancer Res. 84:168-174(1993).
//
RX   PubMed=12794755; DOI=10.1002/ijc.11184;
RA   Endoh H., Yatabe Y., Shimizu S., Tajima K., Kuwano H., Takahashi T.,
RA   Mitsudomi T.;
RT   "RASSF1A gene inactivation in non-small cell lung cancer and its
RT   clinical implication.";
RL   Int. J. Cancer 106:45-51(2003).
//