ID   ACC-LC-319
AC   CVCL_7012
SY   ACC-LC319; Aichi Cancer Center-Lung Cancer-319
DR   BTO; BTO_0004887
DR   cancercelllines; CVCL_7012
DR   Cosmic; 934459
DR   Cosmic; 1089222
DR   Cosmic; 2647636
DR   IARC_TP53; 18790
DR   Wikidata; Q54608121
RX   PubMed=7834619;
RX   PubMed=11583962;
RX   PubMed=12794755;
RX   PubMed=19806789;
CC   Population: Japanese.
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000045116; Zygosity=Unspecified (PubMed=12794755).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro71fs (c.211delC); Zygosity=Unspecified (PubMed=12794755).
DI   NCIt; C3512; Lung adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_7011 ! ACC-LC-314
SX   Sex unspecified
AG   Age unspecified
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 15
//
RX   PubMed=7834619;
RA   Washimi O., Nagatake M., Osada H., Ueda R., Koshikawa T., Seki T.,
RA   Takahashi T., Takahashi T.;
RT   "In vivo occurrence of p16 (MTS1) and p15 (MTS2) alterations
RT   preferentially in non-small cell lung cancers.";
RL   Cancer Res. 55:514-517(1995).
//
RX   PubMed=11583962; DOI=10.1016/S0002-9440(10)62521-7; PMCID=PMC1850523;
RA   Haruki N., Harano T., Masuda A., Kiyono T., Takahashi T.,
RA   Tatematsu Y., Shimizu S., Mitsudomi T., Konishi H., Osada H.,
RA   Fujii Y., Takahashi T.;
RT   "Persistent increase in chromosome instability in lung cancer:
RT   possible indirect involvement of p53 inactivation.";
RL   Am. J. Pathol. 159:1345-1352(2001).
//
RX   PubMed=12794755; DOI=10.1002/ijc.11184;
RA   Endoh H., Yatabe Y., Shimizu S., Tajima K., Kuwano H., Takahashi T.,
RA   Mitsudomi T.;
RT   "RASSF1A gene inactivation in non-small cell lung cancer and its
RT   clinical implication.";
RL   Int. J. Cancer 106:45-51(2003).
//
RX   PubMed=19806789; DOI=10.3727/096504009789745511;
RA   Otsuka S., Hanibuchi M., Ikuta K., Yano S., Goto H., Ogino H.,
RA   Yamada T., Kakiuchi S., Nishioka Y., Takahashi T., Sone S.;
RT   "A bone metastasis model with osteolytic and osteoblastic properties
RT   of human lung cancer ACC-LC-319/bone2 in natural killer cell-depleted
RT   severe combined immunodeficient mice.";
RL   Oncol. Res. 17:581-591(2009).
//