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Cellosaurus BET-3M (CVCL_6F11)

[Text version]
Cell line name BET-3M
Synonyms Bronchial Epithelium transformed with pRSV-T 3M
Accession CVCL_6F11
Resource Identification Initiative To cite this cell line use: BET-3M (RRID:CVCL_6F11)
Comments Characteristics: Cell line positive for alternative lengthening of telomeres (ALT+) (CelloPub=CLPUB00712; PubMed=19935656).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRSV-T).
Derived from site: In situ; Lung, bronchus, epithelium; UBERON=UBERON_0002031.
Cell type: Epithelial cell of bronchus; CL=CL_0002328.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_6F09 ! BET-3A
CVCL_6F10 ! BET-3B
CVCL_UI61 ! BET-3K
CVCL_UI62 ! BFT-3B
CVCL_UI63 ! BFT-3K
Category Transformed cell line
Publications

PubMed=8220580
De Silva R., Reddel R.R.
Similar simian virus 40-induced immortalization frequency of fibroblasts and epithelial cells from human large airways.
Cell. Mol. Biol. Res. 39:101-110(1993)

PubMed=9175740; DOI=10.1093/hmg/6.6.921
Bryan T.M., Marusic L., Bacchetti S., Namba M., Reddel R.R.
The telomere lengthening mechanism in telomerase-negative immortal human cells does not involve the telomerase RNA subunit.
Hum. Mol. Genet. 6:921-926(1997)

CLPUB00712
Henson J.D.
The role of alternative lengthening of telomeres in human cancer.
Thesis PhD (2006); University of Sydney; Sydney; Australia

PubMed=19935656; DOI=10.1038/nbt.1587
Henson J.D., Cao Y., Huschtscha L.I., Chang A.C.-M., Au A.Y.M., Pickett H.A., Reddel R.R.
DNA C-circles are specific and quantifiable markers of alternative-lengthening-of-telomeres activity.
Nat. Biotechnol. 27:1181-1185(2009)

Cross-references
Encyclopedic resources Wikidata; Q54796084
Entry history
Entry creation23-Feb-2016
Last entry update10-Sep-2024
Version number11