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Cellosaurus STA-WT-1 (CVCL_6D82)

[Text version]
Cell line name STA-WT-1
Synonyms STA-WT1; WT; St. Anna Kinderspital-Wilms Tumor-1
Accession CVCL_6D82
Resource Identification Initiative To cite this cell line use: STA-WT-1 (RRID:CVCL_6D82)
Comments From: Children's Cancer Research Institute; Vienna; Austria.
Derived from site: In situ; Kidney; UBERON=UBERON_0002113.
Sequence variations
  • Gene deletion; HGNC; HGNC:11103; SMARCB1; Zygosity=Heterozygous (PubMed=9671307).
  • Mutation; HGNC; HGNC:11103; SMARCB1; Simple; p.Gly317Aspfs*3 (c.950delG); Zygosity=Heterozygous (PubMed=9671307; PubMed=16945155).
Disease Kidney Wilms tumor (NCIt: C40407)
Nephroblastoma (ORDO: Orphanet_654)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 1Y9M
Category Cancer cell line
Publications

PubMed=9671307; DOI=10.1038/28212
Versteege I., Sevenet N., Lange J., Rousseau-Merck M.-F., Ambros P.F., Handgretinger R., Aurias A., Delattre O.
Truncating mutations of hSNF5/INI1 in aggressive paediatric cancer.
Nature 394:203-206(1998)

PubMed=10397258
Rousseau-Merck M.-F., Versteege I., Legrand I., Couturier J., Mairal A., Delattre O., Aurias A.
hSNF5/INI1 inactivation is mainly associated with homozygous deletions and mitotic recombinations in rhabdoid tumors.
Cancer Res. 59:3152-3156(1999)

PubMed=11782423; DOI=10.1093/emboj/21.1.31; PMCID=PMC125819
Craig E., Zhang Z.-K., Davies K.P., Kalpana G.V.
A masked NES in INI1/hSNF5 mediates hCRM1-dependent nuclear export: implications for tumorigenesis.
EMBO J. 21:31-42(2002)

PubMed=16945155; DOI=10.1186/1742-4690-3-56; PMCID=PMC1592304
Sorin M., Yung E., Wu X.-H., Kalpana G.V.
HIV-1 replication in cell lines harboring INI1/hSNF5 mutations.
Retrovirology 3:56.1-56.15(2006)

Cross-references
Encyclopedic resources Wikidata; Q54955810
Polymorphism and mutation databases Cosmic; 802241
Entry history
Entry creation23-Feb-2016
Last entry update19-Dec-2024
Version number10