Cellosaurus IPEC-J2 MDR1 (CVCL_6C41)
| Cell line name | IPEC-J2 MDR1 |
|---|---|
| Accession | CVCL_6C41 |
| Resource Identification Initiative | To cite this cell line use: IPEC-J2 MDR1 (RRID:CVCL_6C41) |
| Comments | Characteristics: Can be used to screen drug compounds for interactions with human efflux pump P-glycoprotein (P-gp). Genetic integration: Method=Transfection; Gene=HGNC; HGNC:40; ABCB1. Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; S.alboniger pac (PuroR). Derived from site: In situ; Small intestine, jejunum; UBERON=UBERON_0002115. Cell type: Enterocyte; CL=CL_0000584. |
| Species of origin | Sus scrofa (Pig) (NCBI Taxonomy: 9823) |
| Hierarchy | Parent: CVCL_2246 (IPEC-J2) |
| Sex of cell | Sex unspecified |
| Age at sampling | <1D |
| Category | Spontaneously immortalized cell line |
| Web pages | http://healthsciences.ku.dk/news/new-2016/copenhagen-researchers-develop-novel-cell-line-for-screening-of-brain-drugs/ |
| Publications | PubMed=26651362; DOI=10.1021/acs.molpharmaceut.5b00874 |
| Cross-references | |
| Encyclopedic resources | Wikidata; Q54897970 |
| Entry history | |
| Entry creation | 23-Feb-2016 |
| Last entry update | 19-Dec-2024 |
| Version number | 10 |