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Cellosaurus LTEP-a2 (CVCL_6929)

[Text version]
Cell line name LTEP-a2
Synonyms LTEP-A2; LTEP a2; LTEP-a-2; LTEPa2
Accession CVCL_6929
Resource Identification Initiative To cite this cell line use: LTEP-a2 (RRID:CVCL_6929)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=26116706). Originally thought to originate from a 46 year old female patient with a lung adenocarcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00576.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Miscellaneous: Formerly the CCRID database had an entry describing this cell line (3131C0001000700033). It was one of the sources for the STR profile of this entry.
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): CCRID; PubMed=26116706

Markers:
AmelogeninX
CSF1PO9,10
D2S133817
D3S135815,18
D5S81811,12
D6S104318,19
D7S8208,12
D8S117912
D12S39120,25
D13S31712,13.3
D16S5399,10
D18S5116
D19S43313,14
D21S1127,28
FGA21
Penta D8,15
Penta E7,17
TH017
TPOX8,12
vWA16,18

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
Publications

PubMed=6872840
Wang H., Lai B.-T., Zhan Q.-P., He L.-X., Tian G.-Q., Huang Z.-Y., Be Z.-Y., Kao J.
Establishment of two human pulmonary adenocarcinoma cell lines (LTEP-a-1, LTEP-a-2) and their biologic properties.
Zhonghua Zhong Liu Za Zhi 5:85-88(1983)

PubMed=2988714
Wang H., Lai B.-T., Zhan X.-P., Liu G.-Z., He L.-X., Tian G.-Q., Huang Z.-Y., Bo Z.-Y., Wu B.-Q., Tang Y.
Establishment of five human pulmonary carcinoma cell lines and their biologic properties.
Zhonghua Yi Xue Za Zhi 65:208-211(1985)

PubMed=3471311; DOI=10.1016/0165-4608(87)90066-5
Fan Y.-S., Li P.
Cytogenetic studies of four human lung adenocarcinoma cell lines.
Cancer Genet. Cytogenet. 26:317-325(1987)

PubMed=1889334
He B.
Invasion of human lung adenocarcinoma cell line LTEP-a2 into various organs of different species.
Zhonghua Zhong Liu Za Zhi 13:16-19(1991)

PubMed=26116706; DOI=10.1096/fj.14-266718
Ye F., Chen C.-G., Qin J., Liu J., Zheng C.-Y.
Genetic profiling reveals an alarming rate of cross-contamination among human cell lines used in China.
FASEB J. 29:4268-4272(2015)

Cross-references
Cell line collections (Providers) CCTCC; GDC0209
Encyclopedic resources Wikidata; Q54903172
Polymorphism and mutation databases Cosmic; 2664118
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number17