ID   HPC-Y5
AC   CVCL_6918
DR   cancercelllines; CVCL_6918
DR   CCRID; 4201PAT-CCTCC00102
DR   Cosmic; 730520
DR   Wikidata; Q54890261
RX   DOI=10.4172/2324-9293.1000104;
RX   PubMed=2208167;
RX   PubMed=7961102;
RX   PubMed=8288629;
CC   Population: Japanese.
CC   Doubling time: 33 hours (PubMed=2208167).
CC   Sequence variation: Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (PubMed=7961102).
CC   Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   57Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 21
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RX   DOI=10.4172/2324-9293.1000104;
RA   Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R.,
RA   Saeger H.-D.;
RT   "Distribution of characteristic mutations in native ductal
RT   adenocarcinoma of the pancreas and pancreatic cancer cell lines.";
RL   Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013).
//
RX   PubMed=2208167;
RA   Yamaguchi N., Yamamura Y., Koyama K., Ohtsuji E., Imanishi J.,
RA   Ashihara T.;
RT   "Characterization of new human pancreatic cancer cell lines which
RT   propagate in a protein-free chemically defined medium.";
RL   Cancer Res. 50:7008-7014(1990).
//
RX   PubMed=7961102; DOI=10.1111/j.1349-7006.1994.tb02898.x; PMCID=PMC5919355;
RA   Suwa H., Yoshimura T., Yamaguchi N., Kanehira K., Manabe T.,
RA   Imamura M., Hiai H., Fukumoto M.;
RT   "K-ras and p53 alterations in genomic DNA and transcripts of human
RT   pancreatic adenocarcinoma cell lines.";
RL   Jpn. J. Cancer Res. 85:1005-1014(1994).
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RX   PubMed=8288629; DOI=10.1016/S0021-9258(17)42180-6;
RA   Yamaguchi N., Hattori K., Oh-eda M., Kojima T., Imai N., Ochi N.;
RT   "A novel cytokine exhibiting megakaryocyte potentiating activity from
RT   a human pancreatic tumor cell line HPC-Y5.";
RL   J. Biol. Chem. 269:805-808(1994).
//