Cellosaurus cell line HPC-Y0 (CVCL

Cellosaurus HPC-Y0 (CVCL_6912)

Cross-references
Cell line name	HPC-Y0
Synonyms	HPC-YO; HPCY0
Accession	CVCL_6912
Secondary accession	CVCL_A067
Resource Identification Initiative	To cite this cell line use: HPC-Y0 (RRID:CVCL_6912)
Comments	Population: Japanese. Doubling time: 28 hours (PubMed=2208167). Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations	Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Heterozygous (PubMed=7961102). Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro152Argfs*18 (c.455delC); ClinVar=VCV000634779; Zygosity=Unspecified (PubMed=7961102).
Disease	Pancreatic acinar cell carcinoma (NCIt: C7977) Acinar cell carcinoma of pancreas (ORDO: Orphanet_424046)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	62Y
Category	Cancer cell line
Publications	PubMed=2208167 Yamaguchi N., Yamamura Y., Koyama K., Ohtsuji E., Imanishi J., Ashihara T. Characterization of new human pancreatic cancer cell lines which propagate in a protein-free chemically defined medium. Cancer Res. 50:7008-7014(1990) PubMed=7961102; DOI=10.1111/j.1349-7006.1994.tb02898.x; PMCID=PMC5919355 Suwa H., Yoshimura T., Yamaguchi N., Kanehira K., Manabe T., Imamura M., Hiai H., Fukumoto M. K-ras and p53 alterations in genomic DNA and transcripts of human pancreatic adenocarcinoma cell lines. Jpn. J. Cancer Res. 85:1005-1014(1994) DOI=10.4172/2324-9293.1000104 Wagenhauser M.U., Ruckert F., Niedergethmann M., Grutzmann R., Saeger H.-D. Distribution of characteristic mutations in native ductal adenocarcinoma of the pancreas and pancreatic cancer cell lines. Cell Biol. Res. Ther. 2:1000104.1-1000104.5(2013)
Cell line databases/resources	cancercelllines; CVCL_6912
Encyclopedic resources	Wikidata; Q54890252
Polymorphism and mutation databases	Cosmic; 730529
Entry history
Entry creation	04-Apr-2012
Last entry update	19-Dec-2024
Version number	19