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Cellosaurus HB611 (CVCL_6907)

[Text version]
Cell line name HB611
Synonyms HB 611
Accession CVCL_6907
Resource Identification Initiative To cite this cell line use: HB611 (RRID:CVCL_6907)
Comments Population: Japanese.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:2514; CTNNB1; Simple; p.Gly34Val (c.101G>T); ClinVar=VCV000017582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Ala159Asp (c.476C>A); ClinVar=VCV001026335; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Asn239Asp (c.715A>G); ClinVar=VCV000234036; Zygosity=Heterozygous (from parent cell line).
Disease Hepatoblastoma (NCIt: C3728)
Hepatoblastoma (ORDO: Orphanet_449)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1296 (HuH-6 Clone 5)
Sex of cell Male
Age at sampling 1Y
Category Cancer cell line
STR profile Source(s): CCRID=1102HUM-NIFDC00072

Markers:
AmelogeninX,Y
CSF1PO10,11
D3S135814,17
D5S8188,11
D7S82011,12
D8S117910,11
D13S3178,12
D16S53910,11
D18S5113,21
D21S1129,30
FGA19,24
Penta D9,13
Penta E10,16
TH017,8
TPOX8
vWA14,17

Run an STR similarity search on this cell line
Publications

PubMed=3025872; DOI=10.1073/pnas.84.2.444; PMCID=PMC304224
Tsurimoto T., Fujiyama A., Matsubara K.-i.
Stable expression and replication of hepatitis B virus genome in an integrated state in a human hepatoma cell line transfected with the cloned viral DNA.
Proc. Natl. Acad. Sci. U.S.A. 84:444-448(1987)

PubMed=8389256; DOI=10.1093/carcin/14.5.987
Hsu I.-C., Tokiwa T., Bennett W.P., Metcalf R.A., Welsh J.A., Sun T.-T., Harris C.C.
p53 gene mutation and integrated hepatitis B viral DNA sequences in human liver cancer cell lines.
Carcinogenesis 14:987-992(1993)

PubMed=7972006; DOI=10.1073/pnas.91.23.11045; PMCID=PMC45163
Okamoto A., Demetrick D.J., Spillare E.A., Hagiwara K., Hussain S.P., Bennett W.P., Forrester K., Gerwin B.I., Serrano M., Beach D.H., Harris C.C.
Mutations and altered expression of p16INK4 in human cancer.
Proc. Natl. Acad. Sci. U.S.A. 91:11045-11049(1994)

Cross-references
Cell line databases/resources cancercelllines; CVCL_6907
CCRID; 1102HUM-NIFDC00072
Anatomy/cell type resources BTO; BTO_0001665
Encyclopedic resources Wikidata; Q54881366
Polymorphism and mutation databases Cosmic; 934553
Cosmic; 2668286
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number20