ID   Eca-109
AC   CVCL_6898
SY   Eca109; Eca 109; EC-109; EC109
DR   BTO; BTO:0005758
DR   EFO; EFO_0022422
DR   AddexBio; C0013001/37
DR   CCRID; 1101HUM-PUMC000246
DR   CCRID; 4201HUM-CCTCC00207
DR   CCTCC; GDC0207
DR   ChEMBL-Cells; CHEMBL3308477
DR   ChEMBL-Targets; CHEMBL614668
DR   Cosmic; 932976
DR   Cosmic; 2267320
DR   Cosmic; 2395000
DR   PubChem_Cell_line; CVCL_6898
DR   Wikidata; Q54831919
RX   PubMed=6525939;
RX   PubMed=9531643;
RX   PubMed=24002547;
WW   https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
CC   Problematic cell line: Partially contaminated. Some stocks of this cell line are contaminated with HeLa (ICLAC).
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00611.
CC   Population: Chinese.
CC   Doubling time: 28.57 +- 0.12 hours (PubMed=24002547).
ST   Source(s): CCRID
ST   Amelogenin: X
ST   CSF1PO: 10
ST   D12S391: 19
ST   D13S317: 11
ST   D16S539: 12
ST   D18S51: 12,16
ST   D19S433: 13
ST   D21S11: 30
ST   D2S1338: 17,20
ST   D2S441: 11,13
ST   D3S1358: 17
ST   D5S818: 12
ST   D6S1043: 13
ST   D7S820: 8,12
ST   D8S1179: 13,14
ST   FGA: 25
ST   Penta D: 9
ST   Penta E: 16
ST   TH01: 9
ST   TPOX: 8
ST   vWA: 16,17
DI   NCIt; C4024; Esophageal squamous cell carcinoma
DI   ORDO; Orphanet_99977; Squamous cell carcinoma of the esophagus
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 25
//
RX   PubMed=6525939;
RA   Gao J., Xue K.-X., Li S.-Z., Dong H.-Y.;
RT   "Studies on invasive characteristics of the epithelial cell line of
RT   human esophageal carcinoma (Eca 109) in organ culture by means of
RT   spheroidal aggregates.";
RL   Zhonghua Zhong Liu Za Zhi 6:247-249(1984).
//
RX   PubMed=9531643;
RA   Xiao F., Wang X.-Q., Wang M.-R., Guan X.-Y., Wu M.;
RT   "Molecular cytogenetic study on four human esophageal cancer cell
RT   lines.";
RL   Zhonghua Yi Xue Yi Chuan Xue Za Zhi 15:75-77(1998).
//
RX   PubMed=24002547; DOI=10.3892/ijo.2013.2083;
RA   Wang C., Guo L.-B., Ma J.-Y., Li Y.-M., Liu H.-M.;
RT   "Establishment and characterization of a paclitaxel-resistant human
RT   esophageal carcinoma cell line.";
RL   Int. J. Oncol. 43:1607-1617(2013).
//