ID   CNE-1
AC   CVCL_6888
AS   CVCL_6887
DR   BTO; BTO:0006074
DR   BioSample; SAMN06481108
DR   cancercelllines; CVCL_6888
DR   ChEMBL-Cells; CHEMBL3308055
DR   ChEMBL-Targets; CHEMBL613824
DR   Cosmic; 755504
DR   Cosmic; 923773
DR   Cosmic; 944909
DR   Cosmic; 1193457
DR   Cosmic; 1322946
DR   Cosmic; 2366879
DR   GEO; GSM375845
DR   Progenetix; CVCL_6888
DR   PubChem_Cell_line; CVCL_6888
DR   TOKU-E; 3588
DR   Ubigene; YC-C062
DR   Wikidata; Q54813873
RX   PubMed=206962;
RX   PubMed=1813165;
RX   PubMed=7129938;
RX   PubMed=12645650;
RX   PubMed=18196576;
RX   PubMed=24991015;
CC   Problematic cell line: Contaminated. On the basis of the STR profile (PubMed=18196576) it is identical to CNE-2 and seems to be a hybrid of HeLa and of cell line of unknown origin. This is also confirmed by RNASeq data from PubMed=24991015. Originally thought to originate from a 58 year old female patient with a nasopharyngeal carcinoma.
CC   Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00473.
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): PubMed=18196576
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 10,12,13.3
ST   D16S539: 9,10
ST   D18S51: 13,16
ST   D19S433: 13
ST   D21S11: 27,30
ST   D2S1338: 17,23
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 10,12
ST   D8S1179: 12,16
ST   FGA: 18,21
ST   TH01: 6,7,9
ST   TPOX: 8,12
ST   vWA: 14,16
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0030 ! HeLa
CA   Hybrid cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 22
RX   PubMed=206962; DOI=10.1360/ya1978-21-1-127;
RA   Zeng Y.;
RT   "Establishment of an epitheloid cell line and a fusiform cell line
RT   from a patient with nasopharyngeal carcinoma.";
RL   Sci. Sin. 21:127-134(1978).
RX   PubMed=1813165;
RA   Kong F.-Y., Gao J.;
RT   "The invasive behavior of two human nasopharyngeal carcinoma (NPC)
RT   cell lines CNE-1, CNE-2Z in vitro.";
RL   Zhonghua Bing Li Xue Za Zhi 20:288-291(1991).
RX   PubMed=7129938; DOI=10.1111/j.1601-5223.1982.tb00706.x;
RA   Zhang S.-Z., Wu Y.-T., Zeng Y., Zech L., Klein G.;
RT   "Cytogenetic studies on an epithelioid cell line derived from
RT   nasopharyngeal carcinoma.";
RL   Hereditas 97:23-28(1982).
RX   PubMed=12645650; DOI=10.1016/S0165-4608(02)00657-X;
RA   Wong N., Hui A.B.-Y., Fan B.-L., Lo K.-W., Pang E., Leung S.-F.,
RA   Huang D.P., Johnson P.J.;
RT   "Molecular cytogenetic characterization of nasopharyngeal carcinoma
RT   cell lines and xenografts by comparative genomic hybridization and
RT   spectral karyotyping.";
RL   Cancer Genet. Cytogenet. 140:124-132(2003).
RX   PubMed=18196576; DOI=10.1002/ijc.23374;
RA   Chan S.Y.-Y., Choy K.-W., Tsao S.-W., Tao Q., Tang T., Chung G.T.-Y.,
RA   Lo K.-W.;
RT   "Authentication of nasopharyngeal carcinoma tumor lines.";
RL   Int. J. Cancer 122:2169-2171(2008).
RX   PubMed=24991015; DOI=10.1128/JVI.01457-14;
RA   Strong M.J., Baddoo M., Nanbo A., Xu M., Puetter A., Lin Z.;
RT   "Comprehensive RNA-seq analysis reveals contamination of multiple
RT   nasopharyngeal carcinoma cell lines with HeLa cell genomes.";
RL   J. Virol. 88:10696-10704(2014).