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Cellosaurus ACC-3 (CVCL_6873)

[Text version]
Cell line name ACC-3
Synonyms Acc-3; ACC3
Accession CVCL_6873
Resource Identification Initiative To cite this cell line use: ACC-3 (RRID:CVCL_6873)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=19557180; PubMed=20143388; PubMed=21868764). Originally thought to originate from a 49 year old male patient with a salivary gland adenoid cystic carcinoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00358.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
STR profile Source(s): PubMed=21868764

Markers:
AmelogeninX
CSF1PO9,10
D5S81811,12
D7S8208,12
D13S31712,13.3
D16S5399,10
TH017
TPOX8,12
vWA17,18

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx
https://web.archive.org/web/20110617125837/http://www.accrf.org/pdf/accrf_update_march2009.pdf
Publications

PubMed=10359046; DOI=10.1111/j.1349-7006.1999.tb00749.x; PMCID=PMC5926065
Toyoshima K.-e., Kimura S., Cheng J., Oda Y., Mori K.J., Saku T.
High-molecular-weight fibronectin synthesized by adenoid cystic carcinoma cells of salivary gland origin.
Jpn. J. Cancer Res. 90:308-319(1999)

PubMed=19557180; DOI=10.1371/journal.pone.0006040; PMCID=PMC2698276
Phuchareon J., Ohta Y., Woo J.M., Eisele D.W., Tetsu O.
Genetic profiling reveals cross-contamination and misidentification of 6 adenoid cystic carcinoma cell lines: ACC2, ACC3, ACCM, ACCNS, ACCS and CAC2.
PLoS ONE 4:E6040-E6040(2009)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

PubMed=21868764; DOI=10.1158/1078-0432.CCR-11-0690; PMCID=PMC3229662
Zhao M., Sano D., Pickering C.R., Jasser S.A., Henderson Y.C., Clayman G.L., Sturgis E.M., Ow T.J., Lotan R., Carey T.E., Sacks P.G., Grandis J.R., Sidransky D., Heldin N.-E., Myers J.N.
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites.
Clin. Cancer Res. 17:7248-7264(2011)

DOI=10.4103/2468-5585.200513
Liu N.-N., Zhang S.-L., Chen W.
The cross-contaminated cell lines of adenoid cystic carcinoma: a crucial concern.
Transl. Surg. 2:10-13(2017)

Cross-references
Biological sample resources BioSample; SAMN03151660
Encyclopedic resources Wikidata; Q54608099
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number26