ID   LN-71
AC   CVCL_6842
SY   LN 71; LN71
DR   BTO; BTO_0005776
DR   cancercelllines; CVCL_6842
DR   Cosmic; 849859
DR   Wikidata; Q54902788
RX   PubMed=10416987;
RX   PubMed=21406405;
RX   PubMed=22570425;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Trp146Ter (c.438G>A); ClinVar=VCV000428890; Zygosity=Unspecified (PubMed=10416987).
CC   Derived from site: In situ; Brain, left temporo-parietal junction; UBERON=UBERON_0023852.
ST   Source(s): PubMed=22570425
ST   Amelogenin: X
ST   CSF1PO: 11,12
ST   D13S317: 12,13
ST   D16S539: 9,11
ST   D18S51: 13
ST   D21S11: 29,31.2
ST   D3S1358: 18
ST   D5S818: 12
ST   D7S820: 9,10
ST   D8S1179: 15
ST   FGA: 21,22
ST   Penta D: 10,13
ST   Penta E: 12,14
ST   TH01: 8
ST   TPOX: 8
ST   vWA: 19
DI   NCIt; C3058; Glioblastoma
DI   ORDO; Orphanet_360; Glioblastoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   67Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 19
//
RX   PubMed=10416987; DOI=10.1111/j.1750-3639.1999.tb00536.x; PMCID=PMC8098486;
RA   Ishii N., Maier D., Merlo A., Tada M., Sawamura Y., Diserens A.-C.,
RA   Van Meir E.G.;
RT   "Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor
RT   suppressor genes in human glioma cell lines.";
RL   Brain Pathol. 9:469-479(1999).
//
RX   PubMed=21406405; DOI=10.1158/0008-5472.CAN-10-3112;
RA   Grzmil M., Morin P. Jr., Lino M.M., Merlo A., Frank S., Wang Y.-H.,
RA   Moncayo G., Hemmings B.A.;
RT   "MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-beta
RT   signaling pathway in human glioblastoma.";
RL   Cancer Res. 71:2392-2402(2011).
//
RX   PubMed=22570425; DOI=10.1093/neuonc/nos072; PMCID=PMC3367844;
RA   Bady P., Diserens A.-C., Castella V., Kalt S., Heinimann K.,
RA   Hamou M.-F., Delorenzi M., Hegi M.E.;
RT   "DNA fingerprinting of glioma cell lines and considerations on
RT   similarity measurements.";
RL   Neuro-oncol. 14:701-711(2012).
//