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Cellosaurus WM3670 (CVCL_6799)

[Text version]
Cell line name WM3670
Synonyms WM-3670; WM 3670; WC00119; WC00119A
Accession CVCL_6799
Resource Identification Initiative To cite this cell line use: WM3670 (RRID:CVCL_6799)
Comments Part of: MD Anderson Cell Lines Project.
Part of: Wistar Institute melanoma cell line collection.
Omics: Protein expression by reverse-phase protein arrays.
Omics: Transcriptome analysis by microarray.
Caution: The reported STR profile from Wistar of this cell line was changed at one point between February 2016 when we retrieved them and entered them in the Cellosaurus and May 2018. The major changes were: Amelogenin: X,Y->X and CSF1PO: 11,12->12.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000027.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (Wistar).
  • Mutation; HGNC; 1097; BRAF; Simple; p.Gly469Glu (c.1406G>A) (p.Gly509Glu, c.1526G>A); ClinVar=VCV000013974; Zygosity=Unspecified (Wistar).
  • Mutation; HGNC; 7989; NRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000039648; Zygosity=Unspecified (Wistar).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX
CSF1PO12
D2S133817,25
D3S135816,18
D5S81811
D7S82011
D8S117913
D13S31711,12
D16S5399,12
D18S5114,19
D19S43314,17
D21S1130
FGA18,19
TH016,9
TPOX11
vWA16,18

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
https://tcpaportal.org/mclp/
Publications

PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005
Li J., Zhao W., Akbani R., Liu W.-B., Ju Z.-L., Ling S.-Y., Vellano C.P., Roebuck P., Yu Q.-H., Eterovic A.K., Byers L.A., Davies M.A., Deng W.-L., Gopal Y.N.V., Chen G., von Euw E.M., Slamon D.J., Conklin D., Heymach J.V., Gazdar A.F., Minna J.D., Myers J.N., Lu Y.-L., Mills G.B., Liang H.
Characterization of human cancer cell lines by reverse-phase protein arrays.
Cancer Cell 31:225-239(2017)

Cross-references
Cell line collections (Providers) Coriell; WC00119 - Discontinued
Rockland; WM3670-01-0001
Cell line databases/resources cancercelllines; CVCL_6799
Encyclopedic resources Wikidata; Q54994275
Polymorphism and mutation databases Cosmic; 1812180
Cosmic; 2159436
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number21