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Cellosaurus WM1791C (CVCL_6793)

[Text version]
Cell line name WM1791C
Synonyms WM-1791C; WM 1791C; WM 1791-C; WC00086
Accession CVCL_6793
Resource Identification Initiative To cite this cell line use: WM1791C (RRID:CVCL_6793)
Comments Part of: Wistar Institute melanoma cell line collection.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Not specified.
Sequence variations
  • Gene deletion; HGNC; HGNC:1787; CDKN2A; Zygosity=Homozygous (Wistar).
  • Gene deletion; HGNC; HGNC:1788; CDKN2B; Zygosity=Homozygous (Wistar).
  • Mutation; HGNC; HGNC:1097; BRAF; None_reported; -; Zygosity=- (Wistar).
  • Mutation; HGNC; HGNC:1773; CDK4; Simple; p.Lys22Gln (c.64A>C); ClinVar=VCV000485487; Zygosity=Unspecified (Wistar).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Thr50Ile (c.149_150delinsTT); Zygosity=Unspecified (Wistar).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Glu62Lys (c.184G>A); Zygosity=Unspecified (Wistar).
Disease Cutaneous melanoma (NCIt: C3510)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_C267 ! WM1791A
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Wistar

Markers:
AmelogeninX,Y
CSF1PO11
D2S133817,25
D3S135816,17
D5S81810,11
D7S82010
D8S117913,14
D13S3178,12
D16S53911,13
D18S5117
D19S43312,16.2
D21S1130
FGA19,22
TH016,7
TPOX8,11
vWA15,18

Run an STR similarity search on this cell line
Web pages https://www.wistar.org/our-scientists/meenhard-herlyn
Publications

PubMed=2253310; DOI=10.1007/BF00046337
Herlyn M.
Human melanoma: development and progression.
Cancer Metastasis Rev. 9:101-112(1990)

PubMed=10952317; DOI=10.1038/35020115
Bittner M., Meltzer P.S., Chen Y.-D., Jiang Y., Seftor E.A., Hendrix M.J.C., Radmacher M.D., Simon R.M., Yakhini Z., Ben-Dor A., Sampas N., Dougherty E.R., Wang E., Marincola F.M., Gooden G.C., Lueders J., Glatfelter A., Pollock P.M., Carpten J.D., Gillanders E.M., Leja D., Dietrich K., Beaudry C., Berens M.E., Alberts D.S., Sondak V.K., Hayward N.K., Trent J.M.
Molecular classification of cutaneous malignant melanoma by gene expression profiling.
Nature 406:536-540(2000)

Cross-references
Cell line collections (Providers) Coriell; WC00086 - Discontinued
Rockland; WM1791C-01-0001
Cell line databases/resources cancercelllines; CVCL_6793
Encyclopedic resources Wikidata; Q54994196
Experimental variables resources EFO; EFO_0022370
Gene expression databases GEO; GSM952585
Polymorphism and mutation databases Progenetix; CVCL_6793
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number24