Cellosaurus cell line P493-6 (CVCL

Cellosaurus P493-6 (CVCL_6783)

[Text version]

Cell line name

P493-6

Synonyms

P-493-6; p493-6

Accession

CVCL_6783

Resource Identification Initiative

To cite this cell line use: P493-6 (RRID:CVCL_6783)

Comments

Characteristics: The expression of the MYC gene is under the control of a tetracycline regulated promoter.
Doubling time: ~36 hours (DSMZ=ACC-915).
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:7553; MYC.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Proteomics; Subcellular; Cell surface.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Cell type: B-cell; CL=CL_0000236.

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_W845 (EREB2-5)

Sex of cell

Sex unspecified

Age at sampling

Age unspecified

Category

Transformed cell line

STR profile

Source(s): DSMZ=ACC-915; Millipore=SCC279

Markers:

Amelogenin	X
CSF1PO	9,12
D2S1338	17,21
D3S1358	15,18
D5S818	11,12
D7S820	8
D8S1179	9,13
D13S317	11,12
D16S539	12
D18S51	13
D19S433	13,14
D21S11	28,32.2
FGA	22
Penta D	11,13
Penta E	12,14
TH01	8,9.3
TPOX	8
vWA	14,18

Publications

PubMed=10956386; DOI=10.1002/1097-0215(20000915)87:6<787::AID-IJC4>3.0.CO;2-6
Pajic A., Spitkovsky D., Christoph B., Kempkes B., Schuhmacher M., Staege M.S., Brielmeier M., Ellwart J.W., Kohlhuber F., Bornkamm G.-W., Polack A., Eick D.
Cell cycle activation by c-myc in a Burkitt lymphoma model cell line.
Int. J. Cancer 87:787-793(2000)

PubMed=25894527; DOI=10.1371/journal.pone.0121314; PMCID=PMC4404347
Bausch-Fluck D., Hofmann A., Bock T., Frei A.P., Cerciello F., Jacobs A., Moest H., Omasits U., Gundry R.L., Yoon C., Schiess R., Schmidt A., Mirkowska P., Hartlova A.S., Van Eyk J.E., Bourquin J.-P., Aebersold R., Boheler K.R., Zandstra P.W., Wollscheid B.
A mass spectrometric-derived cell surface protein atlas.
PLoS ONE 10:e0121314.1-e0121314.22(2015)

Cross-references

Cell line collections (Providers)

DSMZ; ACC-915
Millipore; SCC279

Cell line databases/resources

DSMZCellDive; ACC-915

Anatomy/cell type resources

BTO; BTO_0003291

Encyclopedic resources

Wikidata; Q54937296

Experimental variables resources

EFO; EFO_0022500

Proteomic databases