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Cellosaurus MM5.2 (CVCL_6687)

[Text version]
Cell line name MM5.2
Accession CVCL_6687
Resource Identification Initiative To cite this cell line use: MM5.2 (RRID:CVCL_6687)
Comments Characteristics: Produces IgA kappa and IgG kappa.
Characteristics: Does not require bone marrow stromal cells for growth.
Derived from site: In situ; Bone marrow; UBERON=UBERON_0002371.
Cell type: B-cell; CL=CL_0000236.
Disease Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_6686 (MM5.1 [Human myeloma])
Sex of cell Male
Age at sampling 55Y
Category Cancer cell line
Web pages http://www.cells-talk.com/index.php/page/copelibrary?key=MM5%2e2
Publications

PubMed=9009094; DOI=10.1038/sj.leu.2400564
Van Riet I., De Greef C., Aharchi F., Woischwill C., De Waele M., Bakkus M.H.C., Lacor P., Schots R., Van Camp B.
Establishment and characterization of a human stroma-dependent myeloma cell line (MM5.1) and its stroma-independent variant (MM5.2).
Leukemia 11:284-293(1997)

DOI=10.1007/0-306-46877-8_4
Jernberg-Wiklund H., Nilsson K.
Multiple myeloma cell lines.
(In book chapter) Human cell culture. Vol. 3. Cancer cell lines part 3; Masters J.R.W., Palsson B.O. (eds.); pp.81-155; Kluwer Academic Publishers; New York; USA (2000)

PubMed=10936422; DOI=10.1016/S0145-2126(99)00195-2
Drexler H.G., Matsuo Y.
Malignant hematopoietic cell lines: in vitro models for the study of multiple myeloma and plasma cell leukemia.
Leuk. Res. 24:681-703(2000)

PubMed=11157491; DOI=10.1182/blood.V97.3.729
Chesi M., Brents L.A., Ely S.A., Bais C., Robbiani D.F., Mesri E.A., Kuehl W.M., Bergsagel P.L.
Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma.
Blood 97:729-736(2001)

Cross-references
Encyclopedic resources Wikidata; Q54906156
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number15