ID   MCF-7M
AC   CVCL_6672
SY   MCF-7 M
DR   cancercelllines; CVCL_6672
DR   Wikidata; Q54904407
RX   PubMed=9671407;
RX   PubMed=10811993;
CC   Population: Caucasian.
CC   Doubling time: 1.4 days (PubMed=9671407).
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 4172; GATA3; Simple; p.Asp336Glyfs*17 (c.1006dupG); Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 8975; PIK3CA; Simple; p.Glu545Lys (c.1633G>A); ClinVar=VCV000013655; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
DI   NCIt; C4194; Invasive breast carcinoma of no special type
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0031 ! MCF-7
SX   Female
AG   69Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 20
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RX   PubMed=9671407; DOI=10.1038/sj.onc.1201814;
RA   Sweeney K.J., Swarbrick A., Sutherland R.L., Musgrove E.A.;
RT   "Lack of relationship between CDK activity and G1 cyclin expression in
RT   breast cancer cells.";
RL   Oncogene 16:2865-2878(1998).
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RX   PubMed=10811993; DOI=10.3892/ijo.16.6.1179;
RA   Burow M.E., Weldon C.B., Chiang T.-C., Tang Y., Collins-Burow B.M.,
RA   Rolfe K., Li S.-F., McLachlan J.A., Beckman B.S.;
RT   "Differences in protein kinase C and estrogen receptor alpha, beta
RT   expression and signaling correlate with apoptotic sensitivity of MCF-7
RT   breast cancer cell variants.";
RL   Int. J. Oncol. 16:1179-1187(2000).
//