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Cellosaurus DM93 (CVCL_6629)

[Text version]
Cell line name DM93
Synonyms DM-93; Duke Melanoma 93
Accession CVCL_6629
Resource Identification Initiative To cite this cell line use: DM93 (RRID:CVCL_6629)
Comments From: Duke University Medical Center; Durham; USA.
Characteristics: Pigmented.
Omics: Transcriptome analysis by microarray.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
HLA typing Source: PubMed=10752474
Class I
HLA-AA*02:01,33
HLA-BB*08,49
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_ZL69 (DM93/B7-3)
Category Cancer cell line
Publications

PubMed=2785141; DOI=10.4049/jimmunol.142.9.3329
Darrow T.L., Slingluff C.L. Jr., Seigler H.F.
The role of HLA class I antigens in recognition of melanoma cells by tumor-specific cytotoxic T lymphocytes. Evidence for shared tumor antigens.
J. Immunol. 142:3329-3335(1989)

PubMed=2404572
Crowley N.J., Slingluff C.L. Jr., Darrow T.L., Seigler H.F.
Generation of human autologous melanoma-specific cytotoxic T-cells using HLA-A2-matched allogeneic melanomas.
Cancer Res. 50:492-498(1990)

PubMed=7703289; DOI=10.1089/hum.1995.6.1-87
Fenton R.T., Sznol M., Luster D.G., Taub D.D., Longo D.L.
A phase I trial of B7-transfected or parental lethally irradiated allogeneic melanoma cell lines to induce cell-mediated immunity against tumor-associated antigen presented by HLA-A2 or HLA-A1 in patients with stage IV melanoma. NCI protocol T93-0161. BRMP protocol 9401.
Hum. Gene Ther. 6:87-106(1995)

PubMed=10752474; DOI=10.1007/s002620050015; PMCID=PMC11037162
Slingluff C.L. Jr., Colella T.A., Thompson L., Graham D.D., Skipper J.C.A., Caldwell J., Brinckerhoff L., Kittlesen D.J., Deacon D.H., Oei C., Harthun N.L., Huczko E.L., Hunt D.F., Darrow T.L., Engelhard V.H.
Melanomas with concordant loss of multiple melanocytic differentiation proteins: immune escape that may be overcome by targeting unique or undefined antigens.
Cancer Immunol. Immunother. 48:661-672(2000)

PubMed=14871852; DOI=10.1158/0008-5472.CAN-03-2209
Hogan K.T., Coppola M.A., Gatlin C.L., Thompson L.W., Shabanowitz J., Hunt D.F., Engelhard V.H., Ross M.M., Slingluff C.L. Jr.
Identification of novel and widely expressed cancer/testis gene isoforms that elicit spontaneous cytotoxic T-lymphocyte reactivity to melanoma.
Cancer Res. 64:1157-1163(2004)

PubMed=21654344; DOI=10.1097/CMR.0b013e328343a1d6; PMCID=PMC3131461
Molhoek K.R., Shada A.L., Smolkin M., Chowbina S., Papin J., Brautigan D.L., Slingluff C.L. Jr.
Comprehensive analysis of receptor tyrosine kinase activation in human melanomas reveals autocrine signaling through IGF-1R.
Melanoma Res. 21:274-284(2011)

Cross-references
Anatomy/cell type resources BTO; BTO_0002958
Encyclopedic resources Wikidata; Q54831267
Gene expression databases GEO; GSM1572811
GEO; GSM1572812
GEO; GSM1572813
GEO; GSM1572814
GEO; GSM1572815
GEO; GSM1572816
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17