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Cellosaurus BG1 (CVCL_6570)

[Text version]
Cell line name BG1
Synonyms BG-1; BG-I; Bowman Gray-1; BG-1 FR
Accession CVCL_6570
Resource Identification Initiative To cite this cell line use: BG1 (RRID:CVCL_6570)
Comments Problematic cell line: Partially contaminated. Some stocks are contaminated by MCF-7 (PubMed=22710073; PubMed=25321415).
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00456.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Disease Ovarian adenocarcinoma (NCIt: C7700)
Adenocarcinoma of ovary (ORDO: Orphanet_213504)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling Age unspecified
Category Cancer cell line
STR profile Source(s): Millipore; PubMed=25321415

D21S1129,33.2 (PubMed=25321415)
29,33.2,34.2 (Millipore)
Penta D11,12
Penta E7,12

Run an STR similarity search on this cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v12_distribution.xlsx

PubMed=2910432; DOI=10.1002/1097-0142(19890115)63:2<280::AID-CNCR2820630213>3.0.CO;2-N
Geisinger K.R., Kute T.E., Pettenati M.J., Welander C.E., Dennard Y., Collins L.A., Berens M.E.
Characterization of a human ovarian carcinoma cell line with estrogen and progesterone receptors.
Cancer 63:280-288(1989)

PubMed=9698466; DOI=10.1006/gyno.1998.5039
Maxwell G.L., Risinger J.I., Tong B., Shaw H., Barrett J.C., Berchuck A., Futreal P.A.
Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers.
Gynecol. Oncol. 70:13-16(1998)

PubMed=9769151; DOI=10.1007/s11626-996-0015-9
Baldwin W.S., Curtis S.W., Cauthen C.A., Risinger J.I., Korach K.S., Barrett J.C.
BG-1 ovarian cell line: an alternative model for examining estrogen-dependent growth in vitro.
In Vitro Cell. Dev. Biol. Anim. 34:649-654(1998)

PubMed=22328975; DOI=10.1158/2159-8290.CD-11-0170
Hanrahan A.J., Schultz N., Westfal M.L., Sakr R.A., Giri D.D., Scarperi S., Janakiraman M., Olvera N., Stevens E.V., She Q.-B., Aghajanian C., King T.A., de Stanchina E., Spriggs D.R., Heguy A., Taylor B.S., Sander C., Rosen N., Levine D.A., Solit D.B.
Genomic complexity and AKT dependence in serous ovarian cancer.
Cancer Discov. 2:56-67(2012)

PubMed=22710073; DOI=10.1016/j.ygyno.2012.06.017
Korch C.T., Spillman M.A., Jackson T.A., Jacobsen B.M., Murphy S.K., Lessey B.A., Jordan V.C., Bradford A.P.
DNA profiling analysis of endometrial and ovarian cell lines reveals misidentification, redundancy and contamination.
Gynecol. Oncol. 127:241-248(2012)

PubMed=25321415; DOI=10.1210/me.2014-1229
Li Y., Arao Y., Hall J.M., Burkett S.S., Liu L.-W., Gerrish K., Cavailles V., Korach K.S.
Research resource: STR DNA profile and gene expression comparisons of human BG-1 cells and a BG-1/MCF-7 clonal variant.
Mol. Endocrinol. 28:2072-2081(2014)

Cell line collections (Providers) Millipore; SCC415
Anatomy/cell type resources BTO; BTO:0000177
Biological sample resources BioSample; SAMN03151838
Chemistry resources ChEMBL-Cells; CHEMBL3307815
ChEMBL-Targets; CHEMBL613537
PubChem_Cell_line; CVCL_6570
Encyclopedic resources Wikidata; Q54796229
Gene expression databases GEO; GSM851910
Polymorphism and mutation databases Cosmic; 844351
Cosmic; 1709248
Entry history
Entry creation04-Apr-2012
Last entry update29-Jun-2023
Version number22