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Cellosaurus R201C (CVCL_6540)

[Text version]
Cell line name R201C
Accession CVCL_6540
Resource Identification Initiative To cite this cell line use: R201C (RRID:CVCL_6540)
Comments Problematic cell line: Contaminated/misidentified. Not from strain C57BL/6 as originally assigned but from a C57BL/6 x CBA cross (PubMed=27844419).
Knockout cell: Method=KO mouse; MGI; MGI:88151; Glb1.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; 4298; GLB1 (Note=With p.Arg201Cys).
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6 x CBA.
Hierarchy Parent: CVCL_E938 (SV)
Age at sampling 4D
Category Transformed cell line
Publications

PubMed=11504597; DOI=10.1016/S0387-7604(01)00216-9
Tominaga L., Ogawa Y., Taniguchi M., Ohno K., Matsuda J., Oshima A., Suzuki Y., Nanba E.
Galactonojirimycin derivatives restore mutant human beta-galactosidase activities expressed in fibroblasts from enzyme-deficient knockout mouse.
Brain Dev. 23:284-287(2001)

PubMed=27844419; DOI=10.1007/s11626-016-0104-3; PMCID=PMC5348555
Uchio-Yamada K., Kasai F., Ozawa M., Kohara A.
Incorrect strain information for mouse cell lines: sequential influence of misidentification on sublines.
In Vitro Cell. Dev. Biol. Anim. 53:225-230(2017)

Cross-references
Cell line collections (Providers) JCRB; JCRB1199
Encyclopedic resources Wikidata; Q54949032
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number11