Cellosaurus logo
expasy logo

Cellosaurus CHO-DXB11 CTLA4 Ig-24 (CVCL_6384)

[Text version]
Cell line name CHO-DXB11 CTLA4 Ig-24
Synonyms CTLA4 Ig-24; CTLA4Ig-24
Accession CVCL_6384
Resource Identification Initiative To cite this cell line use: CHO-DXB11 CTLA4 Ig-24 (RRID:CVCL_6384)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-10762.
Genetic integration: Method=Transfection; Gene=HGNC; HGNC:2505; CTLA4 (Note=Extracellular domain fused to the hinge, CH2 and CH3 regions of IgC.gamma.1 domain).
Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

Patent=US5434131
Linsley P.S., Ledbetter J.A., Damle N.K., Brady W.
Chimeric CTLA4 receptor and methods for its use.
Patent number US5434131, 18-Jul-1995

Cross-references
Cell line collections (Providers) ATCC; CRL-10762
CLS; 305014
Cell line databases/resources CLO; CLO_0002634
CCRID; 3101HAMGNHa9
Encyclopedic resources Wikidata; Q54814741
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number17